Results 171 to 180 of about 3,913,833 (314)

Mice infected with Mycobacterium tuberculosis are resistant to acute disease caused by secondary infection with SARS-CoV-2. [PDF]

PLoS Pathog, 2022
Rosas Mejia O, Gloag ES, Li J, Ruane-Foster M, Claeys TA, Farkas D, Wang SH, Farkas L, Xin G, Robinson RT.   +9 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Blood pressure variability and its utility in acute disease and critical illness: a systematic review. [PDF]

BMC Anesthesiol
Zhu X, Shen H.
europepmc   +1 more source

Progressive Course of Chronic Tick-Borne Encephalitis Manifesting as Amyotrophic Lateral Sclerosis-like Syndrome 35 Years after the Acute Disease. [PDF]

Brain Sci, 2022
Volok VP, Gmyl LV, Belyaletdinova IK, Karganova GG, Dekonenko EP.   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Nipah Virus-Associated Neuropathology in African Green Monkeys During Acute Disease and Convalescence. [PDF]

J Infect Dis
Goldin K, Liu Y, Rosenke R, Prado-Smith J, Flagg M, de Wit E.   +5 more
europepmc   +1 more source

Neurographic Evidence of Inflammatory Polyneuropathies in Peri-COVID-19 Circumstances and Their Relationship With Acute Disease Severity and Inflammatory Storm. [PDF]

Cureus, 2022
Hasrat NH, Kadhum HJ, Hashim AR, Yakob ZA, Kadhim LA, Farid HA.   +5 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Functional Capacity Impairment in Long COVID After 17 Months of Severe Acute Disease. [PDF]

Int J Environ Res Public Health
Borges FFDR, Braga ACB, Viana BS, Valente J, Bemfica JM, Sant'Anna T, Goulart CDL, Almeida-Val F, Arêas GPT.   +8 more
europepmc   +1 more source

Vascular and Vasogenic Manifestations of Systemic ANCA-Associated Vasculitis with Renal Involvement in Non-Contrast Brain MRI in Patients with Acute Disease Onset. [PDF]

J Clin Med, 2022
Lubas A, Staszewski J, Maliborski A, Mosakowska M, Spłocharski G, Bilbin-Bukowska A, Wołoszyńska I, Piusińska-Macoch R, Pałka D, Zegadło A, Niemczyk S.   +10 more
europepmc   +1 more source