Results 211 to 220 of about 2,457,521 (267)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec   +6 more
wiley   +1 more source
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Acute Biliary Disease

Surgical Clinics of North America, 2018
Acute biliary disease is a ubiquitous acute surgical complaint. General surgeons managing emergency surgical patients must be knowledgeable and capable of identifying and caring for common presentations. This article discusses the work-up, diagnosis, and management of the varying pathologies that make up biliary disease including cholelithiasis ...
Ann Yih-Ann, Chung   +1 more
openaire   +2 more sources

Cocaine and Acute Vascular Diseases

Current Drug Abuse Reviewse, 2012
Cocaine is one of the most widely used drugs of abuse. Chest pain is the most common side effect requiring emergency visits after cocaine use. Vasoconstriction and platelet activation are the main effects of cocaine in the vasculature. In this brief review, we consider the most important clinical effects of cocaine abuse on the heart, brain and kidney.
De Giorgi A.   +9 more
openaire   +2 more sources

ACUTE HEPATIC DISEASE

Radiologic Clinics of North America, 1997
Acute hepatobiliary dysfunction in children may occur as the result of trauma, infectious hepatitis, biliary obstruction, benign and malignant tumors, and acute vascular obstruction. The targeted and integrated use of modern imaging techniques has made a significant impact in the diagnosis and management of these disorders.
openaire   +2 more sources

ACUTE ABDOMINAL DISEASE

Journal of the American Medical Association, 1954
In general, acute abdominal diseases are of four pathological types: obstructive, infectious, hemorrhagic, and vascular. Frequently a combination of these types is observed, as in obstructions incident to infection and inflammatory edema, and in hemorrhagic pancreatitis. Together, they may produce that most serious emergency: peritonitis.
openaire   +2 more sources

Containing Acute Disease Outbreak

Methods of Information in Medicine, 2005
Summary Objective: The objectives of epidemiological surveillance and research of infectious diseases are to address disease prevention, identify outbreaks and monitor and evaluate control strategies. In this paper, we report on the development of a Geographical Information System (GIS) based on a novel Digital Ring ...
A, Prince, Xin, Chen, K C, Lun
openaire   +2 more sources

Pseudohyponatremia in Acute Liver Disease

The American Journal of the Medical Sciences, 2013
Pseudohyponatremia secondary to hypercholesterolemia is a rare condition. In this study, the case of a 41-year-old woman who presented with acute hepatitis C virus infection and normal serum sodium and cholesterol concentrations is presented. Over the course of several weeks, she developed jaundice due to biopsy-confirmed intrahepatic cholestasis and ...
Hieu, Vo   +3 more
openaire   +2 more sources

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