Results 301 to 310 of about 3,932,966 (340)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Hospital registry in special department for patients with acute cerebrovascular disease

open access: green, 2014
Maslyuk О.А.   +5 more
openalex   +1 more source

Acute Biliary Disease

Surgical Clinics of North America, 2018
Acute biliary disease is a ubiquitous acute surgical complaint. General surgeons managing emergency surgical patients must be knowledgeable and capable of identifying and caring for common presentations. This article discusses the work-up, diagnosis, and management of the varying pathologies that make up biliary disease including cholelithiasis ...
Ann Yih-Ann, Chung   +1 more
openaire   +2 more sources

Containing Acute Disease Outbreak

Methods of Information in Medicine, 2005
Summary Objective: The objectives of epidemiological surveillance and research of infectious diseases are to address disease prevention, identify outbreaks and monitor and evaluate control strategies. In this paper, we report on the development of a Geographical Information System (GIS) based on a novel Digital Ring ...
A, Prince, Xin, Chen, K C, Lun
openaire   +2 more sources

Acute Kidney Disease to Chronic Kidney Disease

Critical Care Clinics, 2021
Acute kidney injury (AKI) and chronic kidney disease are common interconnected syndromes that represent a public health problem. Acute kidney disease (AKD) is defined as the post-AKI status of acute or subacute kidney damage/dysfunction manifested by persistence of AKI beyond 7 to 90 days after the initial AKI diagnosis.
Javier A, Neyra, Lakhmir S, Chawla
openaire   +2 more sources

ACUTE ABDOMINAL DISEASE

Journal of the American Medical Association, 1954
In general, acute abdominal diseases are of four pathological types: obstructive, infectious, hemorrhagic, and vascular. Frequently a combination of these types is observed, as in obstructions incident to infection and inflammatory edema, and in hemorrhagic pancreatitis. Together, they may produce that most serious emergency: peritonitis.
openaire   +2 more sources

Acute Pelvic Inflammatory Disease

Sexually Transmitted Diseases, 1977
The predisposing factors microbial etiology pathogenesis sequelae symptoms diagnosis and treatment of acute pelvic inflammatory disease (PID) are reviewed. Although most cases of PID are not associated with predisposing factors prior PID and the use of the IUD are factors.
S E, Thompson, W D, Hager
openaire   +2 more sources

Acute Valvular Heart Disease

Cardiology Clinics, 2018
Valvular heart disease (VHD) is a common clinical entity. Recognition of decompensated VHD is crucial to instituting appropriate workup and management. Initial evaluation focuses on hemodynamics, peripheral perfusion, volume overload, and active myocardial ischemia.
Varun, Maheshwari   +2 more
openaire   +2 more sources

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