Results 91 to 100 of about 194,975 (319)

Refractory Status Epilepticus Treated With Bilateral Pulvinar Deep Brain Stimulation—A Case Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT New‐onset refractory status epilepticus (NORSE) arises without an identifiable cause or prior epilepsy history, with a 16%–27% mortality rate and significant long‐term neurological sequelae. Neuromodulation such as deep brain stimulation (DBS) targeting the anterior and centromedian thalamic nuclei has shown promise when the traditional ...
Mengxuan Tang, Amerta Bai, Felipe Rodridgues Marques Ferreira, Sandipan Pati, Thaddeus Walczak, Benjamin Miller, Oladi Bentho, Thomas Henry, Ilo Leppik, Minoo Shams, Zhiyi Sha, Zachary Sanger, Theoden I. Netoff, Thomas Lisko, Anant Naik, Robert McGovern III, Sima Patel   +16 more
wiley   +1 more source

Cerebral venous sinus thrombosis secondary to acute cytomegalovirus infection

BMJ Neurology Open, 2023
Background Cerebral venous sinus thrombosis (CVST) is a potentially life-threatening disorder with a number of causes, including viral infections.Case presentation A 25-year-old female patient presented with a non-specific febrile illness, headache and ...
Andrew J Martin
doaj   +1 more source

Risk factors for human brucellosis in northern Tanzania [PDF]

, 2018
Little is known about the epidemiology of human brucellosis in sub-Saharan Africa. This hampers prevention and control efforts at the individual and population levels. To evaluate risk factors for brucellosis in northern Tanzania, we conducted a study of
Biggs, Holly M., Cash-Goldwasser, Shama, Cleaveland, Sarah, Crump, John A., Halliday, Jo E.B., Kazwala, Rudovick R., Lwezaula, Bingileki F., Maro, Venance P., Maze, Michael J., Mmbaga, Blandina T., Muiruri, Charles, Rubach, Matthew P., Saganda, Wilbrod, Shand, Michael C., Sharples, Katrina J., Stoddard, Robyn A.   +15 more
core   +1 more source

Scleritis with Acute Febrile Illness (Sweet's Syndrome)

Annals of Health and Health Sciences, 2014
Sweet's syndrome also known as acute febrile neutrophilic dermatosis, named after Dr Robert Douglas Sweet, is characterized by the abrupt appearance of painful, edematous, and erythematous papules, plaques, or nodules on the skin. Sweet's syndrome can also present with extra-cutaneous manifestations.
R Sandhya, N Inchara
openaire   +1 more source

Clinical Characteristics of Acute Kidney Injury Associated with Tropical Acute Febrile Illness

Tropical Medicine and Infectious Disease, 2023
Tropical acute febrile illness (TAFI) is one of the most frequent causes of acute kidney injury (AKI). The prevalence of AKI varies worldwide because there are limited reports available and different definitions are used. This retrospective study aimed to determine the prevalence, clinical characteristics, and outcomes of AKI associated with TAFI among
Fardosa Dahir Omar, Weerapong Phumratanaprapin, Udomsak Silachamroon, Borimas Hanboonkunupakarn, Natthida Sriboonvorakul, Janjira Thaipadungpanit, Wirichada Pan-ngum   +6 more
openaire   +3 more sources

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Rickettsia conorii infection with fatal complication

Autopsy and Case Reports, 2022
Rickettsial diseases (RD) are a group of endotheliotropic infectious diseases caused by different species of genera Rickettsia. RD are not an uncommon disease and may be misdiagnosed during the evaluation of acute febrile illness due to a lack of ...
Sanjoli Chugh, Priyanka Kumari, Shriya Goel, Manisha Biswal, Inderpaul Singh Sehgal, Aravind Sekar   +5 more
doaj  

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Etiology of acute febrile illness in the peruvian amazon as determined by modular formatted quantitative PCR: a protocol for RIVERA, a health facility-based case-control study

BMC Public Health, 2023
Background The study of the etiology of acute febrile illness (AFI) has historically been designed as a prevalence of pathogens detected from a case series.
Pablo Peñataro Yori, Maribel Paredes Olórtegui, Francesca Schiaffino, Josh M. Colston, Tackeshy Pinedo Vasquez, Paul F. Garcia Bardales, Valentino Shapiama Lopez, Loyda Fiorella Zegarra Paredes, Karin Perez, Greisi Curico, Thomas Flynn, Jixian Zhang, Cesar Ramal Asayag, Graciela Meza Sanchez, Hermann Silva Delgado, Martin Casapia Morales, Wilma Casanova, Bruce Jiu, Richard Oberhelman, Cesar Munayco Escate, Rachel Silver, Olga Henao, Kerry K. Cooper, Jie Liu, Eric R. Houpt, Margaret N. Kosek   +25 more
doaj   +1 more source

Brugada Syndrome: New Implications for Heterozygous Carriers of the Pathogenic SCN5A c.689T>C(p.Ile230Thr) Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in the SCN5A gene and its subunits have been identified in individuals with Brugada Syndrome. One such SCN5A variant, c.689T>C(p.Ile230Thr), was previously reported as disease‐causing only in homozygous individuals, with heterozygous carriers being unaffected.
Shayla Shojaat, Benjamin Hale, Taylor Warner   +2 more
wiley   +1 more source