Circulating levels of soluble MICB in infants with symptomatic primary dengue virus infections. [PDF]
Dengue is the most prevalent arthropod-borne viral illness in humans. A MHC class I polypeptide-related sequence B (MICB) single nucleotide polymorphism (SNP) was previously associated with symptomatic dengue compared to non-dengue causes of acute ...
Daniel H Libraty+4 more
doaj +1 more source
Optimization of Genomic Classifiers for Clinical Deployment: Evaluation of Bayesian Optimization to Select Predictive Models of Acute Infection and In-Hospital Mortality [PDF]
Acute infection, if not rapidly and accurately detected, can lead to sepsis, organ failure and even death. Current detection of acute infection as well as assessment of a patient's severity of illness are imperfect. Characterization of a patient's immune response by quantifying expression levels of specific genes from blood represents a potentially ...
arxiv
A Solution to the Ill-Conditioning of Gradient-Enhanced Covariance Matrices for Gaussian Processes [PDF]
Gaussian processes provide probabilistic surrogates for various applications including classification, uncertainty quantification, and optimization. Using a gradient-enhanced covariance matrix can be beneficial since it provides a more accurate surrogate relative to its gradient-free counterpart.
arxiv
Patterns of age-specific mortality in children in endemic areas of sub-Saharan Africa. [PDF]
Understanding of the age- and season- dependence of malaria mortality is an important prerequisite for epidemiologic models of malaria immunity. However, most studies of malaria mortality have aggregated their results into broad age groups and across ...
Abdullah, Salim+10 more
core +2 more sources
A set of points in $\mathbb{R}^d$ is acute, if any three points from this set form an acute angle. In this note we construct an acute set in $\mathbb{R}^d$ of size at least $2^{d/2}$.
arxiv +1 more source
A journal article on malaria in pregnant women in Tanzania.Women who live in malaria endemic areas may have an asymptomatic background parasitaemia. This asymptomatic parasitaemia can be punctuated by episodes of acute febrile illness due to malaria. The
Magwali, T.L.
core +1 more source
ABSTRACT Background Venetoclax is a potent, oral BCL‐2 inhibitor approved as combination therapy for the treatment of adults with newly diagnosed acute myeloid leukaemia (AML) who are ineligible for intensive chemotherapy. This study evaluated the safety and preliminary efficacy of venetoclax alone or combined with chemotherapy in paediatric and ...
Seth E. Karol+29 more
wiley +1 more source
Family Dysfunction and Self-Medication for Acute Febrile Illness [PDF]
Background: Fever is a common complain from patients globally. Self medication for acute febrile illness is also a common practice but often with severe consequences. The family influences the health of the individuals and hence the community in several ways.
Musa Dankyau, Alexander Adelabu Azonobo
openaire +2 more sources
Incidence of human brucellosis in the Kilimanjaro Region of Tanzania in the periods 2007-2008 and 2012-2014 [PDF]
Background: Brucellosis causes substantial morbidity among humans and their livestock. There are few robust estimates of the incidence of brucellosis in sub-Saharan Africa.
Biggs, Holly M.+13 more
core +1 more source
A new prediction diagnosis model of incomplete Kawasaki disease based on data mining with big data
In this study, based on a medical big data information mining approach, we mined the independent risk factors for incomplete Kawasaki disease prediction by comparing incomplete Kawasaki disease with related febrile illnesses and constructed an auxiliary diagnostic model used to predict incomplete Kawasaki disease.
Zhen Yang+4 more
wiley +1 more source