Cutaneous Adverse Effects of EGFR Therapy in Breast Cancer Treatment
ABSTRACT Breast cancer is among the most common cancers in U.S. women. Epidermal growth factor receptor inhibitors (EGFRIs) target pathways driving tumor growth but frequently cause dermatologic toxicities that impact quality of life and treatment adherence.
Tvisha Devireddy +4 more
wiley +1 more source
Acute generalized exanthematous pustulosis
An 80-year-old woman presented with fever and a generalized, erythematous pruritic eruption of 3 days duration. Four days prior to the eruption, she was treated with terbinafine 250 mg po daily for onychomycosis. She denied any recent viral illness. There was no personal or family history of skin disease.
KARACAN, CAN DEMİR +3 more
openaire +3 more sources
Acute Generalized Exanthematous Pustulosis Induced by Erlotinib (Tarceva) with Superimposed Staphylococcus aureus Skin Infection in a Pancreatic Cancer Patient: A Case Report [PDF]
Acute generalized exanthematous pustulosis (AGEP) is a rare acute reaction that is drug induced in 90% of the cases and characterized by a widespread, sterile pustular rash. Erlotinib, a small-molecule EGFR tyrosine kinase inhibitor, has been approved by
Alali, Fadi +6 more
core +3 more sources
Acute generalized exanthematous pustulosis: European expert consensus for diagnosis and management [PDF]
Acute generalized exanthematous pustulosis (AGEP) is a rare, usually drug‐induced, acute pustular rash. Despite the lack of strong data supporting the effectiveness of topical or systemic corticosteroids in this drug reaction, they are widely used.
Barbaud, A +24 more
core +6 more sources
A Pediatric Case of Acute Generalized Pustular Eruption without Streptococcal Infection
Generalized pustular lesions characterized by acute onset with fever occur in pustulosis acuta generalisata, acute generalized exanthematous pustulosis, and generalized pustular psoriasis.
Nobuko Tabata, Hideka Yoshizawa
doaj +1 more source
Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini +10 more
wiley +1 more source
Acute generalized exanthematous pustulosis induced by ceftriaxone with positive patch testing
Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous reaction. In over 90% of patients it is an adverse reaction to drugs. Delayed-type (type IV) hypersensitivity seems to play an important role in its pathophysiology.
Ana Gabriela Lopes +2 more
doaj +1 more source
Drug‐Induced Periocular and Ocular Surface Disorders: An EAACI Position Paper
ABSTRACT Various systemic and topical medications can induce ocular and periocular cutaneous adverse effects (AEs), ranging from mild to severe. These AEs may lead to ocular surface (OS) damage and, in some cases, life‐threatening complications. Drug‐induced ocular adverse reactions are generally classified into two primary categories: toxic reactions ...
Andrea Leonardi +16 more
wiley +1 more source
Acute generalised exanthematous pustulosis secondary to cotrimoxazole or tenofovir [PDF]
Cutaneous adverse drug reactions are a common complication of antiretroviral therapy and of drugs used to treat opportunistic infections.
Black, J +4 more
core +4 more sources
ABSTRACT Hydroxychloroquine (HCQ) is a common treatment for recurrent implantation failure (RIF), which may be associated with diverse side effects. We report a case of a 36‐year‐old RIF3 pregnant female through in vitro fertilization (IVF) presented to the emergency department with painful, itchy, macular, erythematous, blanchable, and exfoliative ...
Hatav Ghasemi Tehrani +4 more
wiley +1 more source

