Results 71 to 80 of about 3,355 (200)

Evaluation of Diagnosis, Cross‐Reactivity, and Risk Factors in Pediatric Patients With Macrolide Allergy

open access: yesClinical and Translational Allergy, Volume 15, Issue 9, September 2025.
ABSTRACT Background Macrolide antibiotics are generally considered safe in children, but allergic reactions can still occur. This study aims to evaluate the sensitivity and specificity of intradermal test (IDT) used to detect macrolide allergy in pediatric patients, investigate the rate of cross‐reactivity between clarithromycin and azithromycin, and ...
Güler Yıldırım   +8 more
wiley   +1 more source

Unerwünschte Arzneimittelreaktionen an der Haut: Zwischen trivial und fatal [PDF]

open access: yes, 2018
Zusammenfassung: Unerwünschte Arzneimittelwirkungen stellen ein häufiges medizinisches Problem dar. Insbesondere die Überempfindlichkeitsreaktionen sind wegen ihrer dosisunabhängigen, nicht vorhersehbaren Natur häufig beeindruckend und verunsichernd. Die
Bircher, A., Scherer, K.
core  

Rare delayed hypersensitivity reactions to contrast media:Severe cutaneous adverse reactions [PDF]

open access: yes
The risk of developing a severe delayed cutaneous reaction (SCAR) is very low following iodine-based contrast medium (ICM) administration and extremely low following gadolinium-based contrast agent (GBCA) administration.
Dekkers, Ilona A.   +4 more
core   +1 more source

Acute Generalized Exanthematous Pustulosis Caused by Daptomycin [PDF]

open access: yes, 2011
Daptomycin, a lipopeptide antibiotic with similar action as vancomycin, is used to treat complicated skin and soft tissue infections caused by resistant Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, penicillin-resistant ...
Carpenter   +8 more
core   +2 more sources

Paediatric Acute Generalised and Localised Exanthematous Pustulosis: A Systematic Review

open access: yes
JEADV Clinical Practice, EarlyView.
Miranda K. Branyiczky   +6 more
wiley   +1 more source

Hypersensitivity Reactions to Gadolinium‐Based Contrast Agents: Update From an Allergist's Point of View

open access: yesClinical and Translational Allergy, Volume 15, Issue 8, August 2025.
ABSTRACT Background The increasing use of Magnetic Resonance Imaging (MRI) has led to a rise in the administration of gadolinium‐based contrast agents (GBCAs), accompanied by a growing number of reported adverse events (AEs). Objective This review aims to provide an updated overview of hypersensitivity reactions (HSRs) to GBCAs, focusing on diagnostic ...
Francesca Losa   +14 more
wiley   +1 more source

Acute generalized exanthematous pustulosis induced by piroxicam

open access: yesRevista Alergia México, 2016
Background: Between 62 and 90% of cases of acute generalized exanthematous pustulosis are caused by drugs. Its onset is rapid with generalized pustules, fever, and blood neutrophil count over 7000; pustules resolve spontaneously in less than 15 days.
Ingrid Bissinger   +2 more
doaj   +1 more source

The Role of Hydroxychloroquine in the Management of Rheumatic Disorders: A Comprehensive Review

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.
ABSTRACT A drug preferred for its antimalarial effect called hydroxychloroquine (HCQ) has long been used to manage and avoid malaria. Nevertheless, its exact mode of action is still unknown. HCQ works through a variety of strategies to influence distinct molecular and cellular pathways.
Ilker Ates   +4 more
wiley   +1 more source

Hydroxychloroquine‐induced repetitive atypical pustular drug eruptions in the same patient separated by 12 years

open access: yesClinical Case Reports, 2023
Key Clinical Message Hydroxychloroquine (HCQ) has been reported to cause pustular drug eruptions such as acute generalized exanthematous pustulosis (AGEP) and putular psoriasis (PP). Clinical differentitation of these entities is often difficult.
Jeffrey Chen   +4 more
doaj   +1 more source

Endotypes in Immune Mediated Drug Reactions: Present and Future of Relevant Biomarkers. An EAACI Task Force Report

open access: yesAllergy, Volume 80, Issue 7, Page 1831-1847, July 2025.
ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga   +7 more
wiley   +1 more source

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