Results 261 to 270 of about 1,128,690 (346)

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Clinical profiles and prognostic impact of residual intravascular and tissue congestion in acute heart failure. [PDF]

Eur J Heart Fail
Ceelen DCH, Ter Maaten JM, Voordes GHD, Cotter G, Davison BA, Filippatos G, Pang PS, Gimpelewicz C, Cleland JGF, Felker GM, Greenberg B, Givertz MM, O'Conner CM, Teerlink JR, Metra M, Voors AA.   +15 more
europepmc   +1 more source

Impact of prior pacemaker implantation on length of stay in acute diastolic heart failure: a propensity score-matched analysis

Ashot Batikyan
openalex   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Cardioimmunologic response patterns after an acute heart failure event: Design and first results of AHF-ImmunoCS. [PDF]

ESC Heart Fail
Beyersdorf N, Afshar B, Pelin D, Bauser M, Kaiser E, Lamers J, Pätkau J, Heil M, Göpfert D, Hepp H, Al Hassan W, Kerkau T, Kerwagen F, Jahns R, Boivin-Jahns V, Frantz S, Ramos G, Hofmann U, Störk S, Morbach C.   +19 more
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Intermedin prevents acute heart failure following acute kidney injury by alleviating inflammatory responses. [PDF]

Ren Fail
He Y, Jing S, Zhang K, Yao K, Niu J, Ge Y, Su X, Qiao X.   +7 more
europepmc   +1 more source

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

Fibroblast Has2 limits acute heart failure following myocardial infarction in male mice. [PDF]

Physiol Rep
Little DT, Brittian KR, Howard C, Pendergraft E, Colley C, Chen N, Yamaguchi Y, Singhal R, Moore JB, Wysoczynski M, Nong Y, Jones SP.   +11 more
europepmc   +1 more source