Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Newly Diagnosed Infection After Admission for Acute Heart Failure: From the KCHF Registry
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background No studies have explored the association between newly diagnosed infections after admission and clinical outcomes in patients with acute heart failure.
Yuta Seko +26 more
doaj +1 more source
Combination diuretic therapy in acute heart failure [PDF]
, 2023 Yanguo Xin, Jiayu Li, Hongwei Li
openalex +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Burning issues in acute heart failure management
South African Family Practice, 2019 In general, heart failure is the end-stage manifestation of cardiovascular disease and is an important and increasing cause of morbidity worldwide. Acute heart failure, whether of new onset or an exacerbation of chronic heart failure, causes sudden ...
J. A. Ker, K. Outhoff
doaj +1 more source
Acute decompensated heart failure is routinely treated as a cardiopulmonary syndrome. [PDF]
PLoS ONE, 2013 Heart failure as recognized and treated in typical practice may represent a complex condition that defies discrete categorizations. To illuminate this complexity, we examined treatment strategies for patients hospitalized and treated for decompensated ...
Kumar Dharmarajan +7 more
doaj +1 more source
Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure [PDF]
, 2006 Overactivation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) contributes to the development of cell dysfunction and tissue injury in various pathophysiological conditions associated with oxidative and nitrosative stress, including myocardial ...
Cziraki, A. +5 more
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
The correlation between the improvement of dyspnoea condition and the decrease b-line counts in the observation of nitrate therapy for acute heart failure [PDF]
Biotika, 2018 Acute heart failure is common in emergency department. Patients with acute heart failure generally come with dyspnoea. Diagnosing acute heart failure should be done rapidly so that therapy can be given immediately.
Sebastian A. +3 more
doaj
Long-term impact of remote monitoring after hospitalisations for acute decompensated heart failure: a systematic review and meta-analysis of randomised controlled trials [PDF]
, 2023 Mariana Clemente +8 more
openalex +1 more source