Results 61 to 70 of about 4,638,625 (299)

Burning issues in acute heart failure management

South African Family Practice, 2019
In general, heart failure is the end-stage manifestation of cardiovascular disease and is an important and increasing cause of morbidity worldwide. Acute heart failure, whether of new onset or an exacerbation of chronic heart failure, causes sudden ...
J. A. Ker, K. Outhoff
doaj   +1 more source

Acute decompensated heart failure is routinely treated as a cardiopulmonary syndrome. [PDF]

PLoS ONE, 2013
Heart failure as recognized and treated in typical practice may represent a complex condition that defies discrete categorizations. To illuminate this complexity, we examined treatment strategies for patients hospitalized and treated for decompensated ...
Kumar Dharmarajan, Kelly M Strait, Tara Lagu, Peter K Lindenauer, Mary E Tinetti, Joanne Lynn, Shu-Xia Li, Harlan M Krumholz   +7 more
doaj   +1 more source

Newly Diagnosed Infection After Admission for Acute Heart Failure: From the KCHF Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background No studies have explored the association between newly diagnosed infections after admission and clinical outcomes in patients with acute heart failure.
Yuta Seko, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Masayuki Shiba, Erika Yamamoto, Yusuke Yoshikawa, Yugo Yamashita, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Toshikazu Jinnai, Akihiro Komasa, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Mamoru Toyofuku, Yutaka Furukawa, Kenji Ando, Kazushige Kadota, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura   +26 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The brain in heart failure [PDF]

, 2004
After atrial fibrillation, heart failure is the second most frequent cardiac association of stroke. Deteriorating left ventricular systolic function appears to increase the risk of cardioembolic stroke in heart failure.
Pullicino, Patrick
core   +1 more source

Lessons Learned in Acute Heart Failure [PDF]

European Journal of Heart Failure, 2017
Abstract Acute heart failure (HF) is a global pandemic with more than one million admissions to hospital annually in the US and millions more worldwide. Post-discharge mortality and readmission rates remain unchanged and unacceptably high.
Cheema B, Ambrosy AP, Kaplan RM, Senni M, Fonarow GC, Chioncel O, Butler J, Gheorghiade M.   +7 more
openaire   +5 more sources

The correlation between the improvement of dyspnoea condition and the decrease b-line counts in the observation of nitrate therapy for acute heart failure [PDF]

Biotika, 2018
Acute heart failure is common in emergency department. Patients with acute heart failure generally come with dyspnoea. Diagnosing acute heart failure should be done rapidly so that therapy can be given immediately.
Sebastian A., Imowanto Y., Setijowati N., Santoso M.I.E.   +3 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The EuroHeart Failure survey programme—a survey on the quality of care among patients with heart failure in Europe Part 1: patient characteristics and diagnosis [PDF]

, 2003
The European Society of Cardiology (ESC) has published guidelines for the investigation of patients with suspected heart failure and, if the diagnosis is proven, their subsequent management.
van Gilst, WH, Eastaugh, Joanne, Cohen-Solal, A., Gilst, W. H. van, Gavazzi, A, Freemantle, N, Cleland, JG, Gavazzi, A., Hobbs, Frederick, Moiseyev, VS, Dietz, R, van Gilst, W.H., Cleland, J.G., Hobbs, R, Korewicki, J., Follath, F., Hobbs, R., Mason, J., Eastaugh, J, Cohen-Solal, A, Préda, István, Cleland, JGF, Freemantle, Nick, Madeira, HC, Widimsky, J, Swedberg K Follath, F, Dietz, R., Cleland, J. G. F., Widimsky, J., Swedberg, K, Eastaugh, J., Preda, [No Value], Madeira, H. C., Moiseyev, V. S., Aguilar, JC, Aguilar, J.C., Komajda, M., Freemantle, N., Komajda, M, Preda, I., Korewicki, J, Aguilar, J. C., Mason, J, Madeira, H.C., Preda, I, Moiseyev, V.S., Swedberg, K., Follath, F   +47 more
core   +1 more source

Acute heart failure in patients with hematologic malignancies: A nationwide analysis 2016–2021

SAGE Open Medicine
Background: Acute heart failure affects ~9% of patients with hematological malignancies. This study aimed to evaluate the impact of acute heart failure on in-hospital mortality among patients with hematological malignancies and to identify independent ...
Barath Prashanth Sivasubramanian, Diviya Bharathi Ravikumar, Siva Naga S. Yarrarapu, Ragavendar Saravanabavanandan, Ibthisam Ismail Sharieff, Shashvat Joshi, Deepthi Karunakar, Visalakshi Kannathal Vairavan, Indrajith Devandra Balamurugan, Umabalan Thirupathy, Vikramaditya Samala Venkata, Yash Garg, Aditya Kumar Ghosh   +12 more
doaj   +1 more source