Results 161 to 170 of about 8,879,078 (347)

Cork Hospitals Review Group report November 1992 [PDF]

, 1992
Cork Regional Hospital ("CRH") has a total bed complement of 602 beds (of which 50 are closed) and a staff of 1,500. Annual operating costs are approximately £36m.
Cork Hospitals Review Group
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Assessment of prehospital tracheal intubation technique using initial direct laryngoscopy during videolaryngoscopy: randomized controlled simulated trial

BMC Emergency Medicine
Background In critically ill patients, tracheal intubation may be required in the prehospital setting, where airway management presents unique technical and logistical challenges.
Cédric Cibotto, Mathieu Pasquier, Nicolas Beysard, Frédéric Rouyer, Olivier Grosgurin, Laurent Bourgeois, Elio Erriquez, Ely Braun, Birgit Andrea Gartner, Thibaut Desmettre, Laurent Suppan   +10 more
doaj   +1 more source

The association between multi-disciplinary staffing levels and mortality in acute hospitals: a systematic review. [PDF]

Hum Resour Health, 2023
Dall'Ora C, Rubbo B, Saville C, Turner L, Ball J, Ball C, Griffiths P.   +6 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study)

BMJ Open
Introduction Sickle cell disease (SCD) is one of the most common genetic diseases in the world, annually affecting approximately 310 000 births and causing >100 000 deaths.
Thomas Agoritsas, Alain Gervaix, Sylvain Boet, Pierre Cougoul, Cyril Sahyoun, Jerôme Stirnemann, Benoît Desgraz, Olivier Grosgurin, Jean-Luc Reny, Jacques Serratrice, Yves Chalandon, Marc Ansari, Pierre Louge, Tamara Mann, Combescure Christophe, Kaveh Samii, Rodrigue Pignel, Giovanna Cannas, Laurent Cimasoni, Thierry Joffre, Claude Lae, Marie-Anne Magnan, Etienne Menager, Annie Momo Bona, Marc-Alain Panchard, Michel Pellegrini, Beatrice Riu   +26 more
doaj   +1 more source

Involvement, topics, and roles of nurses in shared decision-making with patients with dementia in acute hospitals: An integrative review. [PDF]

Nurs Open, 2023
Keuning-Plantinga A, Stoffels J, Roodbol PF, Finnema EJ, Van Munster BC.   +4 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Ireland's hospitals 1930-1955

, 1956
This book details the Irish hospital activities funded by the Hospitals' Trust (1940) Ltd between 1930 and 1955, along with photographs of the hospitals ...
Hospitals' Trust (1940) Ltd
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BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source