Results 121 to 130 of about 3,479 (173)
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Seminars in Liver Disease, 1998
Acute intermittent porphyria (AIP) is transmitted as an autosomal dominant disorder with incomplete penetrance. Recent population studies suggest that the prevalence of asymptomatic heterozygotes for a mutant AIP gene may be in the range of 1 in 2,000. Clinical manifestations include abdominal pain and neurological dysfunctions.
D A, MALOOLY +3 more
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Acute intermittent porphyria (AIP) is transmitted as an autosomal dominant disorder with incomplete penetrance. Recent population studies suggest that the prevalence of asymptomatic heterozygotes for a mutant AIP gene may be in the range of 1 in 2,000. Clinical manifestations include abdominal pain and neurological dysfunctions.
D A, MALOOLY +3 more
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Best Practice & Research Clinical Gastroenterology, 2005
Acute intermittent porphyria (AIP) is characterised by neurovisceral crises the most common clinical presentation of which is abdominal pain. It is an autosomal dominant condition with incomplete penetrance and is potentially life-threatening. The key point in management is to suspect and confirm the diagnosis as early as possible in order to treat the
Herrick, Ariane L., McColl, Kenneth E L
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Acute intermittent porphyria (AIP) is characterised by neurovisceral crises the most common clinical presentation of which is abdominal pain. It is an autosomal dominant condition with incomplete penetrance and is potentially life-threatening. The key point in management is to suspect and confirm the diagnosis as early as possible in order to treat the
Herrick, Ariane L., McColl, Kenneth E L
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Acute intermittent porphyria in pregnancy
International Journal of Gynecology & Obstetrics, 1989A 27-year-old, previously healthy normotensive woman was admitted for hyperemesis gravidarum and treated with intravenous fluids and metoclopramide. Thereafter, a neuropsychiatric syndrome developed, with acute asymmetrical axonal motor-sensory polyneuropathy and marked anxiety, depression, irritability, and memory and concentration difficulties ...
R, Milo +4 more
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Australian and New Zealand Journal of Surgery, 1973
This rare inherited disease presents with abdominal pain, psychiatric symptoms and neuropathies. Because it may mimic an acute surgical (or less frequently, psychiatric) emergency, it is important in clinical practice. The complication of respiratory paralysis, with a mortality of over 90%, is almost solely due to aggravation of an attack by drugs ...
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This rare inherited disease presents with abdominal pain, psychiatric symptoms and neuropathies. Because it may mimic an acute surgical (or less frequently, psychiatric) emergency, it is important in clinical practice. The complication of respiratory paralysis, with a mortality of over 90%, is almost solely due to aggravation of an attack by drugs ...
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Hyperinsulinemia in Acute Intermittent Porphyria
Hormone and Metabolic Research, 1985Diabetic oral glucose tolerance test together with hyperinsulinemia in a patient with decompensated acute intermittent porphyria is contrasted to normal findings in compensated acute intermittent porphyria (AIP). Results point to the essential role of insulin for the depression of porphyrin precursor overproduction as a mediator of the "glucose effect".
F, Sixel-Dietrich, F, Verspohl, M, Doss
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Australasian Annals of Medicine, 1959
SummaryA family in which 11 cases of acute intermittent porphyria were found in three consecutive generations has been studied. Evidence is presented that inheritance was by an autosomal dominant gene.The usefulness of the Watson and Schwartz test in such a study and in the diagnosis of acute cases is discussed.
D H, CURNOW, E H, MORGAN, G A, SARFATY
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SummaryA family in which 11 cases of acute intermittent porphyria were found in three consecutive generations has been studied. Evidence is presented that inheritance was by an autosomal dominant gene.The usefulness of the Watson and Schwartz test in such a study and in the diagnosis of acute cases is discussed.
D H, CURNOW, E H, MORGAN, G A, SARFATY
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ACUTE INTERMITTENT PORPHYRIA WITH CONVULSIONS
Journal of the American Medical Association, 1958This case of acute intermittent porphyria is presented because of the occurrence of convulsive seizures as the only neurological manifestation, as well as several other unusual features. The porphyrins are pigments composed of four pyrrole rings connected by four methane bridges.
I, FINKELMAN, A, SUMNER, H, VERDE
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Chlorambucil and Acute Intermittent Porphyria
Clinical Oncology, 2002A 54-year-old women with quiescent acute intermittent porphyria (AIP) developed low-grade non-Hodgkin's lymphoma. She was successfully treated with chlorambucil without any significant rise in urinary proto-porphyrins. The case is described and a review of chemotherapy use in AIP is presented.
J H, Davies, S J, Whitaker
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