Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu +4 more
wiley +1 more source
Nefrite tubulointersticial associada à mesalazina [PDF]
Inflammatory bowel disease and its various treatments may affect the kidney in several ways tubulointersticial nephritis is a rare but serious complication of longer-term mesalazine use. There are few cases reported in the literature. We report the first
Cabrita, A. +6 more
core
ABSTRACT Background Vancomycin (VCM), a first‐line treatment option for infections caused by methicillin‐resistant Staphylococcus aureus, has been reported to cause nephrotoxicity even within therapeutic concentration ranges. Traditional therapeutic drug monitoring strategies rely primarily on the area under the concentration–time curve (AUC), without ...
Yoshihiko Matsuki +6 more
wiley +1 more source
Acute tubulointerstitial nephritis and uveitis syndrome: A report on four adult cases
Acute tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease, generally presenting in children and young women. The interstitial nephritis may precede, follow, or develop concurrent to the uveitis.
Yosra Ben Ariba +4 more
doaj +1 more source
Sepsis secondary to cystitis in a guinea pig (Cavia porcellus)
Abstract Cystitis is a frequent, often chronic and recurrent disease in guinea pigs (Cavia porcellus). This report describes a case of a 2‐year‐old, entire, female Abyssinian guinea pig with fatal cystitis. The animal was presented with progressive chronic cystitis and had previously been treated with several antibiotics and analgesics.
Anika Mische +4 more
wiley +1 more source
Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis [PDF]
Extracellular-signal regulated kinase (ERK) activation by MEK plays a key role in many of the cellular processes that underlie progressive kidney fibrosis including cell proliferation, apoptosis and transforming growth factor β1-mediated epithelial to ...
AA Eddy +50 more
core +2 more sources
HISTORY OF THE STUDY OF HEMORRHAGIC FEVER ETIOLOGY WITH RENAL SYNDROME
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral disease of zoonotic nature, characterized by systemic lesions of small vessels, hemorrhagic diathesis, hemodynamic disorders and a peculiar renal disease (interstitial nephritis with acute ...
E. A. TKACHENKO, A. A. ISHMUKHAMETOV
doaj +1 more source
Different behaviour of BK-virus infection in liver transplant recipients [PDF]
Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts ...
MITTERHOFER, Anna Paola +3 more
core +3 more sources
Granulomatous interstitial nephritis due to tuberculosis-a rare presentation
Granulomatous interstitial nephritis (GIN) is an uncommon form of acute interstitial nephritis. We report a young male who presented to us with a rapidly progressing renal failure and massive proteinuria.
Sampathkumar Krishnaswamy +6 more
doaj
Activin–like kinase–3 activity is important for kidney regeneration and reversal of fibrosis [PDF]
Molecules associated with TGF-β superfamily such as BMPs and TGF-β are key regulators of inflammation, apoptosis and cellular transitions. Here, we demonstrate that the BMP receptor activin–like kinase 3 (Alk3) is elevated early in response to kidney ...
Basukonda, Dattatreyamurty +14 more
core +1 more source

