Results 101 to 110 of about 27,769 (249)

PPP2R3C serves as a negative regulator associated with reduced T cell hyperactivation and renal protection in lupus

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Downregulation of PPP2R3C in lupus CD4+ T cells unleashes JNK/c‑Jun and PLCγ1 signalling, driving calcium influx and inflammatory cytokine production. Reconstitution of PPP2R3C expression curbs T cell activation, lowers autoantibody levels and alleviates lupus nephritis, highlighting PPP2R3C as a promising therapeutic candidate. Abstract Background CD4+
Xuan Fang   +8 more
wiley   +1 more source

Acute interstitial nephritis of HIV-positive patients under atazanavir and tenofovir therapy in a retrospective analysis of kidney biopsies [PDF]

open access: yes, 2007
We performed a retrospective analysis on kidney biopsies of 30 human immunodeficiency virus (HIV)-positive patients. Twenty-two of them received highly active antiretroviral therapy (HAART).
Schmid, Simone   +19 more
core   +1 more source

HISTORY OF THE STUDY OF HEMORRHAGIC FEVER ETIOLOGY WITH RENAL SYNDROME

open access: yesМедицинский совет, 2017
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral disease of zoonotic nature, characterized by systemic lesions of small vessels, hemorrhagic diathesis, hemodynamic disorders and a peculiar renal disease (interstitial nephritis with acute ...
E. A. TKACHENKO, A. A. ISHMUKHAMETOV
doaj   +1 more source

Granulomatous interstitial nephritis due to tuberculosis-a rare presentation

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2009
Granulomatous interstitial nephritis (GIN) is an uncommon form of acute interstitial nephritis. We report a young male who presented to us with a rapidly progressing renal failure and massive proteinuria.
Sampathkumar Krishnaswamy   +6 more
doaj  

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Herpes virus infection associated with interstitial nephritis in a beaked whale (Mesoplodon densirostris)

open access: yesBMC Veterinary Research, 2012
Background The capacity for herpesvirus to cause disease in cetaceans is unclear and may be varied depending on the different conditions of individuals and between different species. Kidney pathology and intralesional virus-associated infection have been
Arbelo Manuel   +8 more
doaj   +1 more source

Downstream Treatment Burden and Health‐Care Utilization Following Initiation of GLP‐1 Receptor Agonists or SGLT2 Inhibitors in Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5163-5173, June 2026.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptor agonists and sodium–glucose cotransporter 2 (SGLT2) inhibitors are widely used for the treatment of type 2 diabetes, yet their downstream consequences in routine clinical practice remain incompletely characterized.
Yazan Alhamdan   +2 more
wiley   +1 more source

Impaired potassium and magnesium homeostasis in acute tubulo-interstitial nephritis.

open access: yes, 1985
Although acute tubulo-interstitial nephritis is increasingly recognized as a cause of acute renal failure, little is known about renal tubular function in this disease.
Braden, G L   +2 more
core  

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