Results 61 to 70 of about 37,484 (224)

Evaluating and leveraging large language models in clinical pharmacology and therapeutics assessment: From exam takers to exam shapers

British Journal of Clinical Pharmacology, EarlyView.
Aims In medical education, the ability of large language models (LLMs) to match human performance raises questions about their potential as educational tools. This study evaluates LLMs' performance on Clinical Pharmacology and Therapeutics (CPT) exams, comparing their results to medical students and exploring their ability to identify poorly formulated
Alexandre O. Gérard, Diane Merino, Marc Labriffe, Fanny Rocher, Delphine Viard, Laurence Zemori, Thibaud Lavrut, Erik M. Donker, Joost D. Piët, Jean‐Paul Fournier, Milou‐Daniel Drici, Alexandre Destere   +11 more
wiley   +1 more source

Interstitial nephritis with moderate-to-heavy proteinuria: An unusual combination

Saudi Journal of Kidney Diseases and Transplantation, 2012
Interstitial nephritis with proteinuria >1 g/day is uncommon and almost always the result of drug-induced ATIN with an associated minimal change glomerulonephritis (GN). Here, we present a series of five unusual cases of interstitial nephritis without GN
Biplab Ghosh, Rana Gopal Singh, Usha, Sanjeev Kumar Behura, Ashutosh Soni, Lou Krakpam Sharatchandra, Shivendra Singh   +6 more
doaj   +1 more source

Rosuvastatin-Induced Acute Interstitial Nephritis [PDF]

Case Reports in Nephrology and Dialysis, 2013
We report a case of acute interstitial nephritis (AIN), most likely induced by rosuvastatin, in an 83-year-old male patient. The patient underwent angioplasty of the left internal carotid artery, after which he began a regimen of rosuvastatin (20 mg/day).
Londrino, Francesco, Zattera, Tito, Falqui, Valeria, Corbani, Valentina, Cavallini, Marco, Stefanini, Teseo, Chiappini, Nadia, Ardini, Michela, Martina, Valentina, Rombolà, Giuseppe   +9 more
openaire   +2 more sources

Chemotherapy-related complications in the kidneys and collecting system: an imaging perspective [PDF]

, 2015
Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. The agents most commonly associated with chemotherapy-associated nephrotoxicity are methotrexate, semustine, streptozocin, mithramycin, and cisplatin.
Goodwin, Scott C., Gulati, Rajesh, Jia, Jemianne Bautista, Lall, Chandana, Lamba, Ramit, Tirkes, Temel   +5 more
core   +1 more source

Discovery and validation of a urinary extracellular vesicle protein signature for the diagnosis of renal allograft fibrosis

Interdisciplinary Medicine, EarlyView.
Discovery and validation of a urinary extracellular vesicle protein signature for the diagnosis of renal allograft fibrosis. Abstract Interstitial fibrosis is the best indicator of irreversible or ongoing renal injury after kidney transplantation and faces considerable diagnostic challenges.
Wenxuan Zhao, Yang Xu, Yuewen Wang, Shihao Jin, Wenhui Wang, Zeming Yu, Yanwen Zhang, Yuxin Zhang, Deling Kong, Bing Wang, Zhenzhou Wu, Jie Zhao, Yuebing Wang   +12 more
wiley   +1 more source

Significant kidney impairment in pediatric inflammatory bowel disease and practice points for pediatric gastroenterologists

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Children with inflammatory bowel disease (IBD) have an increased risk of developing kidney disorders, which may cause significant kidney function impairment (SKI) or lead to chronic kidney disease (CKD). In this study we aimed to provide insights in causes and diagnoses of SKI cases and to provide recommendations for pediatric ...
Stephanie A. Vuijk, Renz C. W. Klomberg, Tobias Schwerd, Anne M. Griffiths, Séamus Hussey, Matthew W. Carroll, Petter Malmborg, Protima Deb, Margreet Wessels, Natalia Mouratidou, Stephanie van Biervliet, Michael Friedt, Susie Minson, Femke H. M. Vrieling‐Prince, Nicholas M. Croft, Lissy de Ridder, the PIBD‐SETQuality Safety Registry collaborative group   +16 more
wiley   +1 more source

Severe acute interstitial nephritis secondary to minocycline use in an adolescent girl

SAGE Open Medical Case Reports, 2020
Acute interstitial nephritis is an uncommon but classic complication of minocycline therapy for acne. A 14-year-old African American girl was started on oral minocycline for the treatment of acne 6 weeks before presentation. After 4 weeks on minocycline,
Kamal Sharma, Nicholas Geagan, Supatida Tengsupakul   +2 more
doaj   +1 more source

Membranoproliferative glomerulonephritis in patients with chronic venous catheters: a case report and literature review. [PDF]

, 2014
Chronic indwelling catheters have been reported to be associated with membranoproliferative glomerulonephritis (MPGN) via the activation of the classical complement pathway in association with bacterial infections such as coagulase negative ...
Nast, Cynthia C, Pham, Phuong-Chi T, Pham, Phuong-Thu T, Sy, John   +3 more
core   +2 more sources

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

The evolving role of regulatory T cells in Sjögren's disease pathogenesis and the promise of Treg‐based therapies: A comprehensive review

Rheumatology &Autoimmunity, EarlyView.
Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs, Bharath Raj Srinivasan, Himabindu Jayaprakash Narayan, Mirunalini Gobinath, Lekitha Manjunath, Mahabaleshwar Mamadapur   +5 more
wiley   +1 more source