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Treatment of acute ischemic stroke

Journal of Stroke and Cerebrovascular Diseases, 2001
Acute ischemic stroke remains difficult to treat despite the advent of new therapies. The only approved medication to reverse its effects is recombinant tissue plasminogen activator administered intravenously within 3 hours of onset of stroke symptoms--an opportunity that does not often present itself. The principal drawback to thrombolytic therapy for
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Management of Acute Ischemic Stroke

Mayo Clinic Proceedings, 2004
The treatment of acute ischemic stroke has evolved from observation and the passage of time dictating outcome to an approach that emphasizes time from ictus, rapid response, and a dedicated treatment team. We review the treatment of acute ischemic stroke from the prehospital setting, to the emergency department, to the inpatient hospital setting.
Jimmy R, Fulgham   +5 more
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Thrombolysis for Acute Ischemic Stroke

Neurosurgery Clinics of North America, 1997
The use of thrombolytic agents to restore cerebral blood flow is one of the most notable advances in the treatment of ischemic stroke. This article reviews thrombolytic therapy, its limitations, and the techniques by which thrombolytic agents can be delivered.
D M, Landis, R W, Tarr, W R, Selman
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Acute Ischemic Stroke Management

Thrombosis Research, 2000
The use of thrombolytic therapy represents one of many recent developments in the management of acute ischemic stroke. The development of stroke teams and protocols has been driven by these new demands for an urgent response to ischemic stroke. The short time window of 3 hours for therapy with intravenous recombinant tissue plasminogen activator ...
R P, Atkinson, C, DeLemos
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Alteplase for acute ischemic stroke

Expert Review of Cardiovascular Therapy, 2006
Alteplase, an intravenously administered form of recombinant tissue plasminogen activator (rt-PA), remains the only US FDA-approved thrombolytic treatment for acute ischemic stroke within 3 h of symptom onset. Patients treated with intravenous rt-PA are at least 30% more likely to have minimal or no disability at 3 months compared with placebo. Despite
Nicole R, Gonzales, James C, Grotta
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Immunothrombosis in Acute Ischemic Stroke

Stroke
Ischemic stroke is one of the leading causes of disability and mortality worldwide. Thrombosis is the main pathological process of stroke and is therefore an important therapeutic target in stroke prevention. In recent years, with the development of endovascular treatment and therefore retrieving the thrombus for further investigation, evidence is ...
Yan Wang   +4 more
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Imaging of acute ischemic stroke

Emergency Radiology, 2018
For decades, imaging has been a critical component of the diagnostic evaluation and management of patients suspected of acute ischemic stroke (AIS). With each new advance in the treatment of AIS, the role of imaging has expanded in scope, sophistication, and importance in selecting patients who stand to benefit from potential therapies.
Scott, Rudkin   +3 more
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ACUTE ISCHEMIC STROKE THERAPY

Neurologic Clinics, 2000
Acute ischemic stroke is a medical emergency that requires rapid evaluation and treatment. Prehospital and emergency department care can be streamlined to meet those goals. Intravenous rt-PA therapy improves outcome in selected patients with ischemic stroke if given within 3 hours of stroke onset, but offers no benefit beyond that time window.
S L, Hickenbottom, W G, Barsan
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Troponin T in Acute Ischemic Stroke

The American Journal of Cardiology, 2013
Multiple interactions are considered to occur among the various forms of cardiovascular and cerebrovascular diseases. The aim of this study was to assess the serum level profile of cardiac troponin T (cTnT) in patients with acute ischemic stroke (AIS) to evaluate factors associated with increased serum levels of cTnT. Patients with AIS enrolled in this
Michal, Král   +12 more
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Imaging acute ischemic stroke

2016
Acute ischemic stroke is common and often treatable, but treatment requires reliable information on the state of the brain that may be provided by modern neuroimaging. Critical information includes: the presence of hemorrhage; the site of arterial occlusion; the size of the early infarct "core"; and the size of underperfused, potentially threatened ...
R Gilberto, González, Lee H, Schwamm
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