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Thrombolysis for Acute Ischemic Stroke
Physical Medicine and Rehabilitation Clinics of North America, 1999Data generated from randomized controlled trials in the last decade have shown that acute intervention can improve neurologic outcome in patients with ischemic stroke. This article reviews recent studies of systemic and intra-arterial thrombolysis for cerebrovascular disease in detail.
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Management of Acute Ischemic Stroke
Seminars in Respiratory and Critical Care Medicine, 2002Prior to 1995 no proven therapy existed for acute ischemic stroke. In 1996 the U.S. Food and Drug Administration approved the use of intravenous rt-PA in acute stroke based largely on the results of a two-part trial sponsored by the National Institutes of Health and National Institute of Neurological Disorders and Stroke (NIH/NINDS).
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Hypertension in Acute Ischemic Strokes
Archives of Neurology, 1985Most patients with acute ischemic strokes are hypertensive 1 and pose an almost daily dilemma of whether to treat their blood pressure on admission or not. Yatsu and Zivin emphasize the dangers of decreasing brain perfusion further, producing watershed infarction and facilitating thrombus formation by treating hypertension acutely.
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Treatment of Acute Ischemic Stroke
Continuum, 2017This article provides an update on the state of the art of the emergency treatment of acute ischemic stroke with particular emphasis on the alternatives for reperfusion therapy.The results of several randomized controlled trials consistently and conclusively demonstrating that previously functional patients with disabling strokes from a proximal ...
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Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association
Circulation, 2022Zaid I Almarzooq +2 more
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Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association
Circulation, 2020Salim S Virani +2 more
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Stroke genetics informs drug discovery and risk prediction across ancestries
Nature, 2022Aniket Mishra +2 more
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