Results 221 to 230 of about 707,511 (342)

Rictor Ameliorates Acute Antibody‐Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65‐NLRP3 Axis

Advanced Science, EarlyView.
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni, Chengcheng Yang, Junqi Zhang, Zhou Hang, Ming Zheng, Dengyuan Feng, Qinghuan Shen, Jinxu Miao, Xulin Sun, Li Sun, Baixin Shen, Min Gu, Zijie Wang   +12 more
wiley   +1 more source

Research progress on damage-associated molecular patterns in acute kidney injury. [PDF]

Front Immunol
Li J, Hu Z.
europepmc   +1 more source

Elevated urine neutrophil gelatinase-associated lipocalin can diagnose acute kidney injury in patients with chronic kidney diseases [PDF]

, 2008
Meghan E. Sise, Jonathan Barasch, Prasad Devarajan, Thomas L. Nickolas   +3 more
openalex   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Urine pH is associated with the development of acute kidney injury in crush syndrome. [PDF]

Sci Rep
She F, Zhu Q, Guo J, Pang L, Yan L, Wang Y, Liu S.   +6 more
europepmc   +1 more source

Epidemiology of Acute Kidney Injury

, 2008
Jorge CerdaCombining Acute Accent, Norbert Lameire, Paul W. Eggers, Neesh Pannu, Sigehiko Uchino, Haiyan Wang, Arvind Bagga, Adeera Levin   +7 more
openalex   +1 more source

The hunt for the perfect biomarker for acute kidney injury: back to gamma-trace? [PDF]

, 2008
Josephine P. Briggs
openalex   +1 more source

NIR Driven Pd/Cerium Oxide Nano‐Heterojunction for Enhanced Salvaging Sepsis Induced Acute Liver Injury via Reprogramming Redox Homeostasis in Synergy with Inducing Autophagy

Advanced Science, EarlyView.
In vivo SALI therapy is achieved by scavenging intracellular ROS levels, downregulating inflammatory factors expression levels, inducing macrophage M2 directional polarization, and activating Keap1/Nrf‐2/HO‐1 pathway to reprogram redox homeostasis, induce cellular autophagy, reduce systemic inflammation, and promote liver tissue repair. Abstract Sepsis
Tao Qin, Lian Qin, Yang Zhao, Yin Chen, Qianyue Liu, Xiaoguang Lin, Yongfeng Lan, Yaohui Huang, Yan Liu, Ke Zhang, Lifan Pan, Jiaxiao Li, Kunpeng Duan, Hao Liang, Mingjing Yin, Guiyang Fan, Lian Liu, Yu Deng, Lin Liao, Danke Su, Ming Gao, Junyu Lu   +21 more
wiley   +1 more source

Understanding acute kidney injury in cirrhosis: Current perspective. [PDF]

World J Hepatol
Malakar S, Rungta S, Samanta A, Shamsul Hoda U, Mishra P, Pande G, Roy A, Giri S, Rai P, Mohindra S, Ghoshal UC.   +10 more
europepmc   +1 more source

Cystatin C: a promising misunderstood biomarker for the diagnosis of acute kidney injury [PDF]

, 2008
Michele Ferrannini, Gisella Vischini, Nicola Di Daniele   +2 more
openalex   +1 more source