Results 251 to 260 of about 601,423 (296)

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Renal Shear Wave Elastography for Differentiating Vasculitic and Non-Vasculitic Acute Kidney Injury. [PDF]

J Clin Med
Yıldırım F, Mutlu S, Sam Ozdemir M, Yalcin Mutlu M, Temiz A, Tolu S, Akkuzu G, Sevinc Ozgur D, Karaalioglu B, Deniz R, Yıldız G, Bes C.   +11 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Afatinib-associated pseudo-acute kidney injury. [PDF]

Clin Kidney J
Nguyen J, Das D, Shah CV.
europepmc   +1 more source

Acute kidney injury caused by traditional Chinese medicinal scorpion: Case report. [PDF]

Medicine (Baltimore)
Ma R, Zheng B, Han J, Wang J, Cai M.
europepmc   +1 more source

A kappa opioid receptor agonist, difelikefalin, improves acute kidney injury in experimental sepsis models. [PDF]

PLoS One
Sawanobori Y, Nakano D, Kitamura H, Kitada K, Asaga T, Suzuki N, Yamamoto M, Ogino Y, Shirakami G, Nishiyama A.   +9 more
europepmc   +1 more source

DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312. [PDF]

Nat Commun
Fu Y, Xiang Y, Han Y, Cai J, Duan S, Chen A, Dong Z.   +6 more
europepmc   +1 more source