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The Lancet, 2012
Acute kidney injury (formerly known as acute renal failure) is a syndrome characterised by the rapid loss of the kidney's excretory function and is typically diagnosed by the accumulation of end products of nitrogen metabolism (urea and creatinine) or decreased urine output, or both. It is the clinical manifestation of several disorders that affect the
Ronco C, Bellomo R, Kellum JA
+13 more sources
Acute kidney injury (formerly known as acute renal failure) is a syndrome characterised by the rapid loss of the kidney's excretory function and is typically diagnosed by the accumulation of end products of nitrogen metabolism (urea and creatinine) or decreased urine output, or both. It is the clinical manifestation of several disorders that affect the
Ronco C, Bellomo R, Kellum JA
+13 more sources
Annals of Internal Medicine, 2017
Acute kidney injury is a heterogeneous group of conditions characterized by a sudden decrease in glomerular filtration rate, manifested by an increase in serum creatinine concentration or oliguria, and classified by stage and cause. This type of injury occurs in approximately 20% of hospitalized patients, with major complications including volume ...
Andrew S. Levey, Matthew T. James
+8 more sources
Acute kidney injury is a heterogeneous group of conditions characterized by a sudden decrease in glomerular filtration rate, manifested by an increase in serum creatinine concentration or oliguria, and classified by stage and cause. This type of injury occurs in approximately 20% of hospitalized patients, with major complications including volume ...
Andrew S. Levey, Matthew T. James
+8 more sources
Critical Care Medicine, 2008
Diagnosis and classification of acute pathology in the kidney are major clinical problems. Azotemia and oliguria represent not only disease but normal responses of the kidney to extracellular volume depletion or decreased renal blood flow. Changes in urine output and glomerular filtration rate are therefore neither necessary nor sufficient for the ...
Raymond Vanholder +2 more
openaire +5 more sources
Diagnosis and classification of acute pathology in the kidney are major clinical problems. Azotemia and oliguria represent not only disease but normal responses of the kidney to extracellular volume depletion or decreased renal blood flow. Changes in urine output and glomerular filtration rate are therefore neither necessary nor sufficient for the ...
Raymond Vanholder +2 more
openaire +5 more sources
Science Signaling, 2022
The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) regulates cell death. We sought to determine whether DNA-PKcs played a role in the tubular damage that occurs during acute kidney injury (AKI) induced by LPS injection (to mimic sepsis ...
Shiyuan Wang +6 more
semanticscholar +1 more source
The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) regulates cell death. We sought to determine whether DNA-PKcs played a role in the tubular damage that occurs during acute kidney injury (AKI) induced by LPS injection (to mimic sepsis ...
Shiyuan Wang +6 more
semanticscholar +1 more source
Current concepts and advances in biomarkers of acute kidney injury
Critical reviews in clinical laboratory sciences, 2021Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition remains based on changes in serum creatinine and urinary output that do not specifically represent tubular function or injury and that have significant ...
Yumeng Wen, C. Parikh
semanticscholar +1 more source
The Lancet
Acute kidney injury (AKI) is a common, heterogeneous, multifactorial condition, which is part of the overarching syndrome of acute kidney diseases and disorders. This condition's incidence highest in low-income and middle-income countries. In the short term, AKI is associated with increased mortality, an increased risk of complications, extended stays ...
Marlies, Ostermann +5 more
openaire +2 more sources
Acute kidney injury (AKI) is a common, heterogeneous, multifactorial condition, which is part of the overarching syndrome of acute kidney diseases and disorders. This condition's incidence highest in low-income and middle-income countries. In the short term, AKI is associated with increased mortality, an increased risk of complications, extended stays ...
Marlies, Ostermann +5 more
openaire +2 more sources
2010
Abstract Definition—for practical clinical purposes, acute kidney injury (AKI) is defined as a significant decline in renal excretory function occurring over hours or days, detected by either a fall in urinary output or a rise in the serum concentration of creatinine. Oliguria—defined (arbitrarily) as a urinary volume of less than 400 ml/
openaire +1 more source
Abstract Definition—for practical clinical purposes, acute kidney injury (AKI) is defined as a significant decline in renal excretory function occurring over hours or days, detected by either a fall in urinary output or a rise in the serum concentration of creatinine. Oliguria—defined (arbitrarily) as a urinary volume of less than 400 ml/
openaire +1 more source
2011
Acute renal failure, now termed acute kidney injury (AKI), is a common occurrence in the pediatric intensive care unit. It impacts the management decisions and outcomes of critically ill patients. This chapter will review the factors involved in measuring renal function in children and recognizing abnormal renal function. The major clinical subtypes of
William S. Varade, Elif Erkan
openaire +2 more sources
Acute renal failure, now termed acute kidney injury (AKI), is a common occurrence in the pediatric intensive care unit. It impacts the management decisions and outcomes of critically ill patients. This chapter will review the factors involved in measuring renal function in children and recognizing abnormal renal function. The major clinical subtypes of
William S. Varade, Elif Erkan
openaire +2 more sources
Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study
Intensive Care Medicine, 2015E. Hoste +23 more
semanticscholar +1 more source
Onconephrology: The intersections between the kidney and cancer
Ca-A Cancer Journal for Clinicians, 2021Mitchell H Rosner +2 more
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