Results 101 to 110 of about 401,465 (309)

An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell acute lymphoblastic leukemia: a multi-center study of 381 patients

Haematologica, 2008
In acute lymphoblastic leukemia, besides age and white cell count at diagnosis, the cytogenetic abnormalities t(9;22)/BCR-ABL and t(4;11)/MLL-AF4 are important prognostic markers and are often included in the treatment stratification of patients with ...
Hareth Nahi, Hans Hägglund, Thomas Ahlgren, Per Bernell, Mats Hardling, Karin Karlsson, Vladimir Lj Lazarevic, Mats Linderholm, Bengt Smedmyr, Maria Åström, Helene Hallböök   +10 more
doaj   +1 more source

Acute Lymphoblastic Leukemia Detection from Microscopic Images Using Weighted Ensemble of Convolutional Neural Networks [PDF]

arXiv, 2021
Acute Lymphoblastic Leukemia (ALL) is a blood cell cancer characterized by numerous immature lymphocytes. Even though automation in ALL prognosis is an essential aspect of cancer diagnosis, it is challenging due to the morphological correlation between malignant and normal cells.
arxiv  

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.

Journal of Clinical Oncology, 2015
PURPOSE To review the impact of collaborative studies on advances in the biology and treatment of acute lymphoblastic leukemia (ALL) in children and adolescents.
C. Pui, Jun J. Yang, S. Hunger, R. Pieters, M. Schrappe, A. Biondi, A. Vora, A. Baruchel, L. Silverman, K. Schmiegelow, G. Escherich, K. Horibe, Y. Benoît, S. Izraeli, A. Yeoh, D. Liang, J. Downing, W. Evans, M. Relling, C. Mullighan   +19 more
semanticscholar   +1 more source

t(1;4) translocation in a child with acute lymphoblastic leukemia: a case report

Journal of Medical Case Reports, 2023
Background Acute lymphoblastic leukemia is the most common childhood cancer, with an 80% frequency in children between 1 and 10 years old. The outcome and prognosis of acute lymphoblastic leukemia in children depends on various factors, such as age ...
Chaimae El Mahdaoui, Nezha Hda, Bouchra Oukkache, Hind Dehbi, Nisrine Khoubila, Abdellah Madani, Siham Cherkaoui   +6 more
doaj   +1 more source

Novel Pipeline for Diagnosing Acute Lymphoblastic Leukemia Sensitive to Related Biomarkers [PDF]

arXiv, 2023
Acute Lymphoblastic Leukemia (ALL) is one of the most common types of childhood blood cancer. The quick start of the treatment process is critical to saving the patient's life, and for this reason, early diagnosis of this disease is essential. Examining the blood smear images of these patients is one of the methods used by expert doctors to diagnose ...
arxiv  

Cytokine Release Syndrome Grade as a Predictive Marker for Infections in Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia Treated With Chimeric Antigen Receptor T Cells

Clinical Infectious Diseases, 2018
Cytokine release syndrome grade 3 or higher was independently associated with increased risk of subsequent infection and in particular with bloodstream infection in patients with relapsed B-cell acute lymphoblastic leukemia treated with CD19 chimeric ...
J. H. Park, Jae H. Park, F. A. Romero, Y. Taur, Y. Taur, M. Sadelain, M. Sadelain, R. Brentjens, R. Brentjens, T. Hohl, T. Hohl, S. Seo, S. Seo   +12 more
semanticscholar   +1 more source

Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia. [PDF]

, 2018
The role of Hedgehog signaling in normal and malignant T-cell development is controversial. Recently, Hedgehog pathway mutations have been described in T-ALL, but whether mutational activation of Hedgehog signaling drives T-cell transformation is unknown,
A Dagklis, A Dagklis, A El Andaloussi, A Gutierrez, A Sekulic, AA Ferrando, AE Place, AK Fielding, AL Furmanski, AM Kenney, C Reynolds, CH Pui, CJ Neumann, DD Hoff Von, DI Marks, DM Stone, DV Catenacci, E Drakopoulou, E Lindstrom, GW Robinson, H Hahn, H Hahn, HA Zahreddine, HJ Sharpe, I Hofmann, J Briscoe, J Chen, J Gao, J Rodon, J Taipale, JM Goldberg, JS Blackburn, JY Tang, KD Robarge, LV Goodrich, M Aszterbaum, M Duman-Scheel, M Sadelain, M Schrappe, MJ Koudijs, NJ Rowbotham, PD Bhola, PD Stenson, PL So, PM LoRusso, RH Ko, RL Johnson, S Hettmer, SB Kaye, SP Hunger, SS Winter, SV Outram, T Ni Chonghaile, TT Vo, Y Liu   +54 more
core   +1 more source

Hospital acquired pneumonia risk factors in children with Acute Lymphoblastic Leukemia on chemotherapy

Heliyon, 2021
Background: Over the past 10 years, infection has remained as the main cause of illness and mortality among children with Acute Lymphoblastic Leukemia on chemotherapy. The high incidence of Hospital-Acquired Pneumonia in children with Acute Lymphoblastic
Anitha Marllyin Mairuhu, Mia Ratwita Andarsini, Retno Asih Setyoningrum, Andi Cahyadi, Maria Christina Shanty Larasati, I.Dewa Gede Ugrasena, Bambang Permono, Satrio Budiman   +7 more
doaj  

Pediatric Acute Lymphoblastic Leukemia

Hematology, 2003
AbstractThe outcome for children with acute lymphoblastic leukemia (ALL) has improved dramatically with current therapy resulting in an event free survival exceeding 75% for most patients. However significant challenges remain including developing better methods to predict which patients can be cured with less toxic treatment and which ones will ...
Elizabeth A. Raetz, John C. Reed, C. L. Willman, Stella Davies, James R. Downing, William L. Carroll, Dong Joon Min, Mary V. Relling, Deepa Bhojwani   +8 more
openaire   +3 more sources

Marrow transplantation for patients with acute lymphoblastic leukemia in remission [PDF]

, 1979
Thomas Ed, JE Sanders, Nancy Flournoy, F L Johnson, CD Buckner, Clift Ra, A Fefer, BW Goodell, R Storb, PL Weiden   +9 more
openalex   +3 more sources