Results 61 to 70 of about 401,465 (309)

T-cell acute lymphoblastic leukemia

Haematologica, 2009
T-cell acute lymphoblastic leukemia (T-ALL) accounts for about 15% and 25% of ALL in pediatric and adult cohorts respectively.1 Patients usually have high white blood cell counts and may present with organomegaly, particularly mediastinal enlargement and CNS involvement. The biological knowledge of TALL has until recently been rather limited.
CHIARETTI, sabina, FOA, Roberto
openaire   +3 more sources

Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia

Frontiers in Oncology, 2020
Asparagine Synthetase (ASNS) catalyzes the synthesis of the non-essential amino acid asparagine (Asn) from aspartate (Asp) and glutamine (Gln). ASNS expression is highly regulated at the transcriptional level, being induced by both the Amino Acid ...
Martina Chiu, G. Taurino, M. Bianchi, M. Kilberg, O. Bussolati   +4 more
semanticscholar   +1 more source

Acute myelogenous leukemia switch lineage upon relapse to acute lymphoblastic leukemia: a case report [PDF]

, 2009
Acute leukemia, the most common form of cancer in children, accounts for approximately 30% of all childhood malignancies, with acute lymphoblastic leukemia being five times more frequent than acute myeloid leukemia.
Aurora Medina-Sanson, AW Tolcher, B Falini, C Cobaleda, CA Hurwitz, Carlos A Rodriguez-Osorio, CH Pui, DS Krause, E Mantadakis, E Smith, Elisa Dorantes-Acosta, Farina Arreguin-Gonzalez, G Zardo, GA Gagnon, GE Panzer, M Henderson, MH Zarrabi, OP Smith, Rosana Pelayo, RS Welner, S Stass, SA Stass, Stanislaw Sadowinski, T Palomero, TM Harned, TR Golub   +25 more
core   +2 more sources

The prognosis of CALM-AF10-positive adult T-cell acute lymphoblastic leukemias depends on the stage of maturation arrest

Haematologica, 2013
CALM-AF10 (also known as PICALM-MLLT10) is the commonest fusion protein in T-cell acute lymphoblastic leukemia, but its prognostic impact remains unclear.
Raouf Ben Abdelali, Vahid Asnafi, Arnaud Petit, Jean-Baptiste Micol, Céline Callens, Patrick Villarese, Eric Delabesse, Oumedaly Reman, Stephane Lepretre, Jean-Yves Cahn, Gaelle Guillerm, Céline Berthon, Claude Gardin, Bernadette Corront, Thibaut Leguay, Marie-Christine Béné, Norbert Ifrah, Guy Leverger, Hervé Dombret, Elizabeth Macintyre   +19 more
doaj   +1 more source

Multilineage Lymphoblastic Lymphoma as an Initial Presentation of Mixed Phenotype Acute Leukemia

Case Reports in Hematology, 2023
Mixed phenotype acute leukemia (MPAL) is characterized by leukemic blasts that express markers of multiple lineages. Compared with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), MPAL is considered to have a poor treatment outcome ...
Mako Ikeda, Wataru Nakahara, Mizuki Asako, Yuka Umeki, Yoshiki Matsuoka, Takuya Terakawa, Hitomi Matsunaga, Yuki Iwasa, Riko Saito, Yuki Iwama, Takahiro Matsui, Kazumasa Oka, Shuji Ueda   +12 more
doaj   +1 more source

Acute Lymphoblastic Leukemia in Adults

Pediatric Reports, 2011
Acute lymphoblastic leukemia (ALL) is the most frequent neoplastic disease in children, being a rare disease in adults. Many of the advances in pediatric ALL have been through modifications in the doses and schedules of available agents as opposed to the introduction of new compounds.
openaire   +4 more sources

Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice

Haematologica, 2014
Novel therapies are needed for pediatric acute lymphoblastic leukemia resistant to conventional therapy. While emerging data suggest leukemias as possible targets of oncolytic attenuated measles virus, it is unknown whether measles virus can eradicate ...
Nike C. Lühl, Felix Zirngibl, Carmen Dorneburg, Jiwu Wei, Meike Dahlhaus, Thomas F.E. Barth, Lüder H. Meyer, Manon Queudeville, Sarah Eckhoff, Klaus-Michael Debatin, Christian Beltinger   +10 more
doaj   +1 more source

Precision medicine in acute lymphoblastic leukemia

Frontiers in Medicine, 2020
The cure rate of childhood acute lymphoblastic leukemia (ALL) has exceeded 90% in some contemporary clinical trials. However, the dose intensity of conventional chemotherapy has been pushed to its limit.
C. Pui
semanticscholar   +1 more source

Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia

Haematologica, 2010
Although childhood acute lymphoblastic leukemia is the most common pediatric cancer, its etiology remains poorly understood. In an attempt to replicate the findings of 2 recent genome-wide association studies in a French-Canadian cohort, we confirmed the
Jasmine Healy, Chantal Richer, Mathieu Bourgey, Ekaterini A. Kritikou, Daniel Sinnett   +4 more
doaj   +1 more source

Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus [PDF]

, 2016
Although there are high survival rates for children with acute lymphoblastic leukaemia, their outcome is often counterbalanced by the burden of toxic effects.
Attarbaschi, Andishe, Barzilai, Shlomit, Escherich, Gabriele, Frandsen, Thomas Leth, Halsey, Christina, Hough, Rachael, Jeha, Sima, Kato, Motohiro, Liang, Der-Cherng, Mikkelsen, Torben Stamm, Moricke, Anja, Niinimaki, Riitta, Piette, Caroline, Putti, Maria Caterina, Raetz, Elizabeth, Schmiegelow, Kjeld, Silverman, Lewis B., Skinner, Roderick, Tuckuviene, Ruta, van der Sluis, Inge, Zapotocka, Ester   +20 more
core   +2 more sources