The prognostic value of bone marrow lymphocytes in acute lymphocytic leukemia of childhood [PDF]
, 1974 Alexander A. Green
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CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade
Advanced Science, EarlyView.This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou +15 more
wiley +1 more source
Weight status in survivors of childhood acute lymphocytic leukemia in South Korea: a retrospective descriptive study. [PDF]
Child Health Nurs Res, 2023 Kim Y, Bang KS.
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Advanced Science, EarlyView.B‐cell lymphomas are aggressive malignancies with limited treatment options. A bispecific nanosystem (biHSNPs) is developed, leveraging silica nanoplatforms to conjugate antibodies targeting immune effector cells and B‐cell antigens. biHSNPs form artificial immunological synapses, activating cytotoxic responses and suppressing tumor proliferation. This
Yefeng Shen +12 more
wiley +1 more source
Arterial Thromboembolism in a Patient With Cancer With Unclear Etiology
Annals of Internal Medicine: Clinical CasesA 57-year-old man with chronic lymphocytic leukemia presented with acute ischemia of the left lower extremity. The patient was taken for emergent surgical thrombectomy of the common femoral artery and the thrombus was submitted for pathologic evaluation,
Taylor A. Hopper +3 more
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Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities
Advanced Science, EarlyView.The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley +1 more source
A Review of Acute Lymphocytic Leukemia (ALL) in the Pediatric Population: Evaluating Current Trends and Changes in Guidelines in the Past Decade. [PDF]
Cureus, 2023 Ekpa QL +8 more
europepmc +1 more source
Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins. [PDF]
, 1983 S J Korsmeyer +11 more
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Granulocytic Sarcoma as the First Sign of Acute Leukemia in Childhood [PDF]
, 2012 Acute myeloid leukemia (AML) may rarely involve the orbit as a solid tumor termed granulocytic sarcoma. This report describes the case of a child who presented with rapidly progressive unilateral proptosis and was diagnosed as rhabdomyosarcoma.
Singh, T, Sufi, AR
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Information Preserving Component Analysis: Data Projections for Flow Cytometry Analysis
, 2008 Flow cytometry is often used to characterize the malignant cells in leukemia and lymphoma patients, traced to the level of the individual cell. Typically, flow cytometric data analysis is performed through a series of 2-dimensional projections onto the ...
Alfred O. Hero Iii +4 more
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