ResRandSVM: Hybrid Approach for Acute Lymphocytic Leukemia Classification in Blood Smear Images. [PDF]
Diagnostics (Basel), 2023 Acute Lymphocytic Leukemia is a type of cancer that occurs when abnormal white blood cells are produced in the bone marrow which do not function properly, crowding out healthy cells and weakening the immunity of the body and thus its ability to resist ...
Sulaiman A +6 more
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Silencing of Exosomal miR-181a Reverses Pediatric Acute Lymphocytic Leukemia Cell Proliferation
bioRxiv, 2020 Exosomes are cell-generated nano-vesicles (30-150 nm) found in most biological fluids. Major components of their cargo are lipids, proteins, RNA, DNA, and non-coding RNAs.
S. Haque, Sarah R. Vaiselbuh
semanticscholar +1 more source
COVID-19 vaccine efficacy in patients with chronic lymphocytic leukemia
Leukemia, 2021 While randomized controlled trials demonstrated 94–95% efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike messenger RNA (mRNA) vaccines [1, 2], efficacy in immunocompromised patients has not been established.
L. Roeker +17 more
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Pattern Recognition of Acute Lymphoblastic Leukemia (ALL) Using Computational Deep Learning
IEEE Access, 2023 Leukemia is a cancer of blood-producing cells, including the bone marrow. Abnormal white blood cells travel through blood vessels and multiply rapidly. Healthy cells in the body become a minority, and the imbalance increases the chances of infection in ...
Nasmin Jiwani +3 more
semanticscholar +1 more source
Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia
Nature Communications, 2021 Current therapeutic approaches for chronic lymphocytic leukemia (CLL) focus on the suppression of oncogenic kinase signaling. Here, we test the hypothesis that targeted hyperactivation of the phosphatidylinositol-3-phosphate/AKT (PI3K/AKT)-signaling ...
V. Ecker +17 more
semanticscholar +1 more source
Epigenetics of Acute Lymphocytic Leukemia [PDF]
Seminars in Hematology, 2009 The term epigenetics refers to the study of a number of biochemical modifications of chromatin that have an impact on gene expression regulation. Aberrant epigenetic lesions, in particular DNA methylation of promoter associated CpG islands, are common in acute lymphocytic leukemia (ALL).
Guillermo, Garcia-Manero +5 more
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CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia.
New England Journal of Medicine, 2019 The safety of CRISPR (clustered regularly interspaced short palindromic repeats)-based genome editing in the context of human gene therapy is largely unknown.
Lei Xu +22 more
semanticscholar +1 more source
Simultaneous Occurrence of Acute Myeloid Leukemia and Chronic Lymphocytic Leukemia: A Case Report
Liječnički vjesnik, 2023 Concurrent development of acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) is very rare. We present a case of simultaneous CLL and AML in a patient with no prior exposure to cytotoxic agents or irradiation.
Stjepan Galić, Ozren Jakšić
doaj +1 more source
Outcomes of haploidentical stem cell transplantation for chronic lymphocytic leukemia: a retrospective study on behalf of the chronic malignancies working party of the EBMT [PDF]
, 2018 Allogeneic hematopoietic stem cell transplantation (HCT) may result in long-term disease control in high-risk chronic lymphocytic leukemia (CLL). Recently, haploidentical HCT is gaining interest because of better outcomes with post-transplantation ...
Beelen, Dietrich +23 more
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Acute Leukemia Occurring During Chronic Lymphocytic Leukemia [PDF]
Blood, 1970 Abstract Acute leukemia occurred in two of 340 persons with chronic lymphocytic leukemia listed in a registry of leukemia cases among residents of Georgia. One case was acute myeloblastic leukemia; the cell type of the other was disputed.
P, McPhedran, C W, Heath
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