Results 201 to 210 of about 2,092,286 (303)

Leveraging venetoclax‐induced autophagy to enhance AUTAC‐mediated Mcl1 degradation and overcome resistance in acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Ahmed M. Elshazly, Nayyerehalsadat Hosseini, Janakiram R. Vangala, Xiaoyan Hu, Steven Grant, Senthil K. Radhakrishnan   +5 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Clinical Characteristics of SARS-COV-2 Omicron Variant in Acute Myeloid Leukemia and Acute Lymphocytic Leukemia Patients: A Multi-Center Retrospective Study. [PDF]

Cancer Rep (Hoboken)
Wang L, Mi R, Chen L, Liu J, Yang H, Hu M, Xiaoqiang Z, Zhang Y, Xu X, Liu B, Zhao H, Qianyu L, Liu T, Zhenzhu C, Yao J, Yang Y, Wei X.   +16 more
europepmc   +1 more source

From infusion to pills in acute myeloid leukaemia: Reorganizing care beyond the infusion unit

British Journal of Haematology, EarlyView.
Fortunato Morabito, Enrica Antonia Martino, Antonella Bruzzese, Nicola Amodio, Santino Caserta, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Ernesto Vigna, Massimo Gentile   +11 more
wiley   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

A hybrid detection model for acute lymphocytic leukemia using support vector machine and particle swarm optimization (SVM-PSO). [PDF]

Sci Rep
Alsaykhan LK, Maashi MS.
europepmc   +1 more source

Outcomes for post‐transplant relapsed acute lymphoblastic leukaemia in the era of novel therapies: A retrospective multicentre UK study

British Journal of Haematology, EarlyView.
Alexandros Rampotas, Amy A. Kirkwood, Maximillian Brodermann, Nicola Maciocia, Fotios Panitsas, Sridhar Chaganti, Styliani Bouziana, Emma Nicholson, Samantha Drummond, Michelle Lannon, Amy Publicover, Sharon Allen, Isaac Gannon, Andrew J. King, Anne‐Louise Latif, Henry Crosland, Claire Roddie   +16 more
wiley   +1 more source

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

SLAMF6 Enhances the Efficacy of Anti‐PD‐L1 Immunotherapy in CRC Through the STAT1/CXCL10 Signaling Axis

Cancer Science, EarlyView.
SLAMF6 recruits SHP‐2 to activate STAT1, upregulates CXCL10 and PD‐L1, promotes CD8+T cell infiltration, and enhances the efficacy of anti‐PD‐L1 therapy. ABSTRACT As a T‐cell receptor co‐stimulatory protein, signaling lymphocyte activation molecule family 6 (SLAMF6) is a member of the immune cell activating receptor family and is expressed on T cells ...
Yu Wu, Xinhui Lv, Shunhao Zhang, Yafang Chen, Sicong Liu, Feiyang Song, Chunmei Zhao, Guihua Wang, Xudong Wang   +8 more
wiley   +1 more source

A common PTPRC polymorphism impairs memory T‐cell enrichment by CD45RA depletion: Rationale for donor screening

British Journal of Haematology, EarlyView.
Jarmila Stremenova Spegarova, Kay Carruthers, Aneta Ogah, Emma Matthews, Lulu Wang, Angela Grainger, Helen Watson, Rebecca Payne, David Bourn, Jane Matthews, Mary Slatter, Su Han Lum, Sophie Hambleton, Haplo+4Kids Study Team   +13 more
wiley   +1 more source