Outcomes of haploidentical stem cell transplantation for chronic lymphocytic leukemia: a retrospective study on behalf of the chronic malignancies working party of the EBMT [PDF]
, 2018 Allogeneic hematopoietic stem cell transplantation (HCT) may result in long-term disease control in high-risk chronic lymphocytic leukemia (CLL). Recently, haploidentical HCT is gaining interest because of better outcomes with post-transplantation ...
Beelen, Dietrich +23 more
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Morpheaform leukemia cutis in a case of b-cell acute lymphoblastic leukemia - A rare presentation
Indian Journal of Paediatric Dermatology, 2022 Leukemia cutis (LC) is the cutaneous infiltration of neoplastic cells rarely seen with acute lymphocytic leukemia. We report the case of a young female presenting with a morpheaform plaque on the face, subsequently diagnosed with B-cell acute ...
Liza Mohapatra +5 more
doaj +1 more source
Simultaneous Occurrence of Acute Myeloid Leukemia and Chronic Lymphocytic Leukemia: A Case Report
Liječnički vjesnik, 2023 Concurrent development of acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) is very rare. We present a case of simultaneous CLL and AML in a patient with no prior exposure to cytotoxic agents or irradiation.
Stjepan Galić, Ozren Jakšić
doaj +1 more source
The development of acute myelomonocytic leukemia in a patient with acute lymphocytic leukemia [PDF]
Cancer, 1981 A diagnosis of acute lymphocytic leukemia (ALL) was made from a peripheral blood and bone marrow specimen from a 59-year-old woman. Typical-appearing lymphoblasts were positive for periodic acid-Schiff (PAS) reaction, but negative for peroxidase, Sudan black B (SBB) and non-specific esterase (NSE) stains. Lymphoblasts failed to form non-immune rosettes
Leonard Madoff +4 more
openaire +3 more sources
Direct admission to the intensive care unit from the emergency department and mortality in critically ill hematology patients [PDF]
, 2019 Background: The aim of this study was to assess the benefit of direct ICU admission from the emergency department (ED) compared to admission from wards, in patients with hematological malignancies requiring critical care.
Azoulay, Elie +14 more
core +2 more sources
Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia. [PDF]
, 2017 BackgroundThe CXCR4-CXCL12 axis plays an important role in the chronic lymphocytic leukemia (CLL)-microenvironment interaction. Overexpression of CXCR4 has been reported in different hematological malignancies including CLL.
Amaya-Chanaga, Carlos I +18 more
core +4 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2013 OBJECTIVE To detect markers for minimal residual disease monitoring based on conventional polymerase chain reaction for immunoglobulin, T-cell receptor rearrangements and the Sil-Tal1 deletion in patients with acute lymphocytic leukemia. METHODS Fifty-
Juliana Godoy Assumpcao +8 more
doaj +1 more source
Frontiers in Immunology, 2022 The use of chimeric antigen receptor T cells (CAR-Ts) is effective in the treatment of hematological malignancies. It has been reported that HBV is reactivated after CAR-T immunotherapy for refractory/relapsed hematological malignant B-cell tumors ...
Zhihui Li +3 more
doaj +1 more source
Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis [PDF]
, 2010 Background A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous.
A Le Noir +26 more
core +4 more sources
Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia [PDF]
, 2014 Bruton's tyrosine kinase (BTK) is a cytoplasmic protein found in all hematopoietic cell lineages except for T cells. BTK mediates signalling downstream of a number of receptors.
Advani +59 more
core +1 more source