Results 291 to 300 of about 87,634 (337)

Low rates of endothelial cell dysfunction and transplant‐related mortality in 537 children receiving fludarabine–treosulfan conditioning for all transplant indications: A retrospective multicentre study on behalf of the UK Paediatric BMT group

British Journal of Haematology, EarlyView.
Thomas Altmann, Kanchan Rao, Ramya Hanasoge‐Nataraj, Katharine Patrick, Ben Carpenter, Rachael Hough, Anna‐Maria Ewins, Sanjay Tewari, Oana Mirci‐Danicar, Mary Slatter, Robert Wynn, Su Han Lum   +11 more
wiley   +1 more source

Co‐operative epigenetic remodelling by Setd2 deficiency and Kras mutation drives juvenile myelomonocytic leukaemia development and MEK inhibitor sensitivity

British Journal of Haematology, EarlyView.
A proposed model of Setd2 deficiency and KrasG12D/+ mutation synergism in the pathogenesis of juvenile myelomonocytic leukaemia (JMML). KrasG12D/+ mutation instigates constitutive activation of the RAS‐ERK1/2 signalling pathway, and Setd2 ablation in the KrasG12D/+ mutant background further hyperactivates the RAS‐ERK1/2 signalling pathway, leading to ...
Gustave Munyurangabo, Linlin Zhang, Ying Zhou, Peihua Zhang, Xiao Yu, Dou Qu, Dan Yang, Xiaomin Ren, Hongwei Liu, Yonghong Wu, Guangyao Kong, Yi Yang   +11 more
wiley   +1 more source

Has early mortality following single‐unit unrelated cord blood transplantation improved in recent years? A nationwide registry data analysis from 2003 to 2022 in Japan

British Journal of Haematology, EarlyView.
The 100‐day non‐relapse mortality after single‐unit cord blood transplantation significantly declined from 19.6% (2003–2007) to 9.5% (2018–2022), while the 3‐year overall survival improved from 38.8% to 54.4%. Haematopoietic recovery rates improved steadily, with neutrophil engraftment reaching 89.6% and platelet engraftment 78.0% in the most recent ...
Takaaki Konuma, Junya Kanda, Naoyuki Uchida, Masatsugu Tanaka, Fumihiko Kimura, Hideki Nakasone, Yasufumi Uehara, Masahito Tokunaga, Masako Toyosaki, Shigesaburo Miyakoshi, Noriko Doki, Kazuya Ishiwata, Hikaru Kobayashi, Yasushi Onishi, Yasuji Kozai, Koji Kato, Fumihiko Ishimaru, Takahiro Fukuda, Yoshiko Atsuta, Satoshi Takahashi   +19 more
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Cyclophosphamide—A promising solution for refractory ICANS

British Journal of Haematology, EarlyView.
Manan Vora, Himanshu Gujarathi, Hasmukh Jain, Alok Shetty, Vasundhara Patil, Savan Pandey, M. V. Ramya Kumar, Lingaraj Nayak   +7 more
wiley   +1 more source

[Efficacy of allogeneic hematopoietic stem cell transplantation based on a total body irradiation conditioning treatment regimen for adult acute lymphocytic leukemia]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Xiao QQ, Yu XL, Song XC, Hou YX, Deng L, Li WJ, Zhou F.   +6 more
europepmc   +1 more source

Incremental immunogenicity of multiple doses of SARS‐CoV‐2 vaccination in patients with haematological malignancies

British Journal of Haematology, EarlyView.
Abi Vijenthira, Sita Bhella, Katrina Hueniken, Allison M. Wilkin, Michael Sebag, Peng Wang, Lisa K. Hicks, Annette E. Hay, Sarit Assouline, Amaris Balitsky, Graeme Fraser, Joy Mangel, Carolyn Owen, Anthony Reiman, Laurie Sehn, Heather Sutherland, Corey Arnold, Tamara Leite, Erinn McCarthy, Angela Crawley, Curtis Cooper, Marc‐Andre Langlois, C. Arianne Buchan, VIP Study Investigators   +23 more
wiley   +1 more source

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Acute lymphocytic leukemia

Hématologie, 2014
Les leucemies aigues lymphoblastiques (LAL) sont des proliferations malignes de precurseurs lymphoides anormaux bloques a un stade precoce de differenciation. Les LAL de l’enfant et de l’adulte different par leurs caracteristiques et leurs pronostics. L’identification de nouveaux mecanismes d’oncogenese et l’evaluation de la reponse par quantification ...
Martin Gauthier, Diane Lara
openaire   +2 more sources