Results 341 to 350 of about 351,966 (398)

Treatment of Childhood Acute Lymphocytic Leukemia

The Journal of Pediatrics, 1970
Thank you for the honor of sharing in this memorial to Frederick Stohlman. The work I will report today represents the efforts of many physicians and scientists who have tried to understand and control childhood leukemia.
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Acute transformation of chronic lymphocytic leukemia

Medical and Pediatric Oncology, 1984
AbstractA patient with chronic lymphocytic leukemia had typical cell morphology and a characteristic clinical course for 7 years. He then developed progressive disease with a rapidly rising WBC which proved resistant to chemotherapy. The cells resembled lymphoblasts.
A D, Jacobs, R W, Schroff, R P, Gale
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Emerging drugs for acute lymphocytic leukemia

Expert Opinion on Emerging Drugs, 2013
Acute lymphoblastic leukemia (ALL) is typically treated with complex multi-agent chemotherapy regimens over a prolonged time period. Long-term outcomes depend on the age of the patient and the biological characteristics of the leukemic cells. While pediatric patients achieve cure more often than adults, therapy can continue to be improved for all ...
Michael S, Mathisen, Hagop M, Kantarjian, Elias J, Jabbour   +2 more
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PATHOLOGIC DIAGNOSIS OF ACUTE LYMPHOCYTIC LEUKEMIA

Hematology/Oncology Clinics of North America, 2000
With present knowledge, the optimal management of individual patients with acute leukemia requires that every case be studied by morphology, cytochemistry, cytogenetic, immunologic and molecular techniques. An algorithm for diagnostic evaluation and classification of ALL is provided in Fig. 11.
R, Lai, C F, Hirsch-Ginsberg, C, Bueso-Ramos   +2 more
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Nine years' experience with "total therapy" of childhood acute lymphocytic leukemia.

Pediatrics, 1972
Experience with combined chemotherapy and radiotherapy of acute lymphocytic leukemia (ALL) in children is reviewed. Multiple anti-metabolite chemotherapy is effective in prolonging duration of continuous hematological remission.
D. Pinkel, J. Simone, H. Hustu, R. Aur
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Childhood acute lymphocytic leukemia. Study VIII

Cancer, 1978
This controlled study of children with ALL was designed to test the efficacy and toxicity of one-, two-, three- and four-drug therapy during remission and whether more aggressive therapy in the first eight weeks prolongs remission in patients with features associated with a particularly poor prognosis.
R J, Aur, J V, Simone, M S, Verzosa, H O, Hustu, L F, Barker, D P, Pinkel, G, Rivera, G V, Dahl, A, Wood, S, Stagner, C, Mason   +10 more
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Giant mitochondria in acute lymphocytic leukemia

Experimental and Molecular Pathology, 1987
Giant mitochondria were observed in 2 cases among 28 cases of ALL by electron microscopy. The cristae of the giant mitochondria in the leukemic cells were irregularly arranged, decreased in number, and formed concentric circles. Several morphological abnormalities were also observed in the normal mitochondria.
M, Eguchi, Y, Iwama, F, Ochiai, K, Ishikawa, H, Sakakibara, H, Sakamaki, T, Furukawa   +6 more
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Diabetes Insipidus Complicating Acute Lymphocytic Leukemia

Archives of Pediatrics & Adolescent Medicine, 1969
DIABETES insipidus complicating acute leukemia has been reported but rarely. In a comprehensive review Rosensweig and Kendall 1 found 12 such cases, only one of which was in a child. The patient was recorded to have had acute granulocytic leukemia. 2 Of the remaining 11 adult patients, only one had acute lymphocytic leukemia. 3 This report presents the
I J, Malter, S, Gross, T M, Teree
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Lymphocyte glutathione levels in acute leukemia

Clinica Chimica Acta, 1999
The current interest in the clinical significance of the glutathione estimation in leukemia is due to its widespread effect on the cell constituent and cell function of the hematopoietic system. It helps and protects the cells against free radicals and reactive oxygen products.
V, Singh Ghalaut, S, Kharb, P S, Ghalaut, A, Rawal   +3 more
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Infectious Mononucleosis in Acute Lymphocytic Leukemia

JAMA: The Journal of the American Medical Association, 1965
An 18-year-old high-school student was found to have lymphoblastic leukemia at the age of 16 years. Remission was obtained with weekly doses of 2 mg/sq m of body surface of vincristine sulfate and daily doses of 40 mg/ sq m of prednisone. Maintenance treatment with intramuscular administration of methotrexate, 30 mg/sq m twice weekly, was initiated ...
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