Results 41 to 50 of about 33,519 (179)
Small bowel obstruction caused by myeloid sarcoma in a patient with any hematological abnormality is very rare. Myeloid sarcoma occurs most commonly in patients with acute myelogenous leukemia (AML) and less with other hematological disorders.
Bülent Aslan, MD +4 more
doaj +1 more source
CLINICAL MANIFESTATIONS OF SECONDARY APLASIA AFTER CHEMOTHERAPY [PDF]
Objectives. Our aims were to highlight the clinical signs and symptoms of secondary bone marrow aplasia after intensive chemotherapy. Material and methods.
Erzsebet Papp Zsuzsanna +1 more
doaj +1 more source
A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley +1 more source
Applications of Microarray Technology to Acute Myelogenous Leukemia
Microarray technology is a powerful tool, which has been applied to further the understanding of gene expression changes in disease. Array technology has been applied to the diagnosis and prognosis of Acute Myelogenous Leukemia (AML).
Rashmi S. Goswami +4 more
doaj +2 more sources
ABSTRACT APL presenting as an extramedullary mass is exceedingly rare. Here, we describe extramedullary APL causing cauda equina syndrome, underscoring the diagnostic challenges associated with an atypical presentation, highlighting the complexity of distinguishing extramedullary APL from other conditions, and discussing the stepwise approach to ...
Amir Ali +8 more
wiley +1 more source
Basophilia is commonly associated with chronic myelogenous leukemia, notably in the accelerated phase or during blast crisis. It is also associated with other myeloproliferative neoplasms.
Sreejesh Sreedharanunni +2 more
doaj +1 more source
ABSTRACT Objective To investigate the development of oral premalignant and malignant lesions as a major long‐term complication following hematopoietic stem cell transplantation. Methods This single‐center retrospective study identified 17 patients who developed 26 pathology‐confirmed oral premalignant and malignant lesions after hematopoietic stem cell
Pei Hsuan Lu +3 more
wiley +1 more source
Vacuolization as a Novel Approach to Cancer Therapy
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source
Third‐Generation Nanopore Sequencing for Post‐Transplant Chimerism Monitoring
ABSTRACT Post‐transplant chimerism monitoring is a cornerstone of hematopoietic stem cell transplantation (HSCT) follow‐up, providing early and clinically actionable information on engraftment, graft rejection and disease relapse. Analytical strategies have progressively evolved from STR‐based assays towards more sensitive molecular approaches ...
Pascal Pedini +7 more
wiley +1 more source

