Results 91 to 100 of about 387,242 (314)

Out-of-hours primary percutaneous coronary intervention for ST-elevation myocardial infarction is not associated with excess mortality: a study of 3347 patients treated in an integrated cardiac network [PDF]

, 2013
OBJECTIVES: Timely delivery of primary percutaneous coronary intervention (PPCI) is the treatment of choice for ST-segment elevation myocardial infarction (STEMI).
Rathod, Krishnaraj S., Gallagher, Sean M., Gallagher, SM, Bromage, Dan, Wragg, Andrew, Knight, Charles, Wragg, A, Jain, Ajay K., Archbold, AR, Rathod, KS, Bromage, DI, Knight, CJ, Jones, DA, Mathur, Anthony, Jones, Daniel A., Jain, AK, Whitbread, Mark, Whitbread, M, Mathur, A, Archbold, Andrew   +19 more
core   +1 more source

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

Constituent country inequalities in myocardial infarction incidence and case fatality in men and women in the United Kingdom, 1996-2005. [PDF]

, 2010
BACKGROUND: Understanding myocardial infarction (MI) incidence and case fatality trends across the four UK constituent countries is of importance following devolution of the government of health-care services.
E. Grundy, Davies, Alisha Ruth, Smeeth, Liam, D. Nitsch, Davies, AR, Nitsch, D, Nitsch, Dorothea, Smeeth, L, L. Smeeth, Grundy, Emily, A. R. Davies, Grundy, E   +11 more
core   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Correction: Left ventricular function and coronary microcirculation in patients with mild reduced ejection fraction after STEMI

BMC Cardiovascular Disorders, 2022
Yuliang Ma, Lan Wang, Wenying Jin, Tiangang Zhu, Jian Liu, Hong Zhao, Jing Wang, Mingyu Lu, Chengfu Cao, Bailin Jiang   +9 more
doaj   +1 more source

Research Advances in Myocardial Infarction Repair and Cardiac Regenerative Medicine via the Notch Signaling Pathway

Reviews in Cardiovascular Medicine
Acute myocardial infarction is myocardial necrosis caused by acute and persistent ischemia and hypoxia in the coronary artery and severely affects public health.
Songyan Cai, Qingyuan Dai
doaj   +1 more source

Q50, an Iron-Chelating and Zinc-Complexing Agent, Improves Cardiac Function in Rat Models of Ischemia/Reperfusion-Induced Myocardial Injury [PDF]

, 2013
Background: Reperfusion of ischemic myocardium may contribute to substantial cardiac tissue damage, but the addition of iron chelators, zinc or zinc complexes has been shown to prevent heart from reperfusion injury.
Faragó, Nóra, Hirschberg Kristóf, Korkmaz S, Merkely Béla Péter, Radovits, Tamás, Hirschberg, Kristóf, Barnucz E, Karck Matthias, Szabó Gábor, Fábián Gabriella, Gyuris Márió, Puskás László G., Loganathan Sivakkanan, Radovits Tamás, Weymann Alexander, Szabó, Csaba, Fábián, Gabriella, Loganathan, Sivakkanan, Karck, Matthias, Merkely, Béla, Kanizsai Iván, Faragó Nóra, Hegedűs Péter, Korkmaz, Sevil, Li Shiliang, Hegedűs, Péter, Gyuris, Márió, Szabó Csaba, Zubarevich Alina, Li, Shiliang, Puskás, László G., Korkmaz Sevil, Ózsvári, Béla, Zubarevich, Alina, Weymann, Alexander, Li S, Merkely Béla, Barnucz, Enikő, Puskás László, Kanizsai, Iván, Szabó, Gábor, Barnucz Enikő, Loganathan S, Ózsvári Béla   +43 more
core   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Timing of coronary artery bypass grafting after myocardial infarction influences late survivalCentral MessagePerspective

JTCVS Open
Objectives: The role of timing of coronary artery bypass grafting after acute myocardial infarction on early and late outcomes remains uncertain. Methods: We reviewed 1631 consecutive adult patients who underwent isolated coronary artery bypass grafting ...
Sri Harsha Patlolla, MBBS, MS, Juan A. Crestanello, MD, Hartzell V. Schaff, MD, Alberto Pochettino, MD, John M. Stulak, MD, Richard C. Daly, MD, Kevin L. Greason, MD, Joseph A. Dearani, MD, Nishant Saran, MBBS   +8 more
doaj   +1 more source

Comparison of In-hospital Major Adverse Cardiovascular Events in Patients of Acute Inferior Myocardial Infarction With or Without Precordial ST Segment Depression

Majalah Kardiologi Indonesia, 2017
Background: The clinical implications of precordial ST segment depression (PSTD) during acute inferior myocardial infarction has been an area of debate, and still under investigation with conflicting results.
Jaya Suganti, Abdullah Afif Siregar, Harris Hasan   +2 more
doaj   +1 more source