Results 131 to 140 of about 360,402 (292)
Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics
Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan+12 more
wiley +1 more source
Implications of a new clinical classification of acute myocardial infarction. [PDF]
Thurston AJF+4 more
europepmc +2 more sources
Analysis of 150 patients with acute myocardial infarction admitted to an intensive care and study unit. [PDF]
Michael Thomas+2 more
openalex +1 more source
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang+10 more
wiley +1 more source
OBJECTIVE: Recent studies have shown that circulating microRNAs might be useful, novel biomarkers for the diagnosis of acute myocardial infarction. The aims of this study were to evaluate the expression of cardiac-specific miRNAs (miR-1, -133a, -208b ...
Ying-Qing Li+9 more
doaj
Oxygen Affinity of Hemoglobin in Persons with Acute Myocardial Infarction and in Smokers [PDF]
Robert S. Eliot, Hiroshi Mizukami
openalex +1 more source
Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre‐mRNA
This work defines the context‐dependent function of Zc3h12c in macrophages using the Tnfrsf11a‐Cre system. It reveals Zc3h12c's dual mechanism—regulating RNA degradation and alternative splicing—with STAT1 as a key target. The findings elucidate a novel post‐transcriptional pathway and identify STAT1 isoforms as potential therapeutic targets for kidney
Chenyu Li+14 more
wiley +1 more source
Successful External Electrical Defibrillation in Acute Myocardial Infarction [PDF]
Philip R. Nast+2 more
openalex +1 more source
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li+5 more
wiley +1 more source
Survival after left ventricular free wall rupture due to acute myocardial infarction
BACKGROUND: Left ventricular free wall rupture is a frequent catastrophic complication of acute myocardial infarction (AMI) and occurs in 1-3% of patients with acute myocardial infarction; it is the third most common cause of death caused by acute ...
Mahmood Hosseinzadeh-Maleki+3 more
doaj