Results 131 to 140 of about 651,453 (295)

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

Acute myocardial infarction complicated by cardiogenic shock: an algorithm based ECMO program can improve clinical outcomes. [PDF]

, 2016
Objective: Extracorporeal membrane oxygenation (ECMO) in our institution resulted in near total mortality prior to the establishment of an algorithm-based program in July 2010. We hypothesized that an algorithm based ECMO program improves the outcome of
Cavarocchi, MD, Nicholas C., Hirose, MD, Hitoshi, Ruggiero, MD, Nicholas, Tanaka, MD, Daizo, Unai, MD, Shinya   +4 more
core   +1 more source

Autonomous Polymer Frameworks for Sustainable Tissue‐Interfaced Plastic Bioelectronics

Advanced Science, EarlyView.
This review focuses on plastic bioelectronic systems integrated with autonomous polymer frameworks (auto‐POFs) and summarizes recent progress in this field. It provides an in‐depth analysis of the design strategies and operational mechanisms of auto‐POFs, highlighting their pivotal role in enhancing the sustainability and interfacial adaptability of ...
Elvis K. Boahen, Zhengyang Kong, So Young Kim, Hayoung Oh, Hanseo Yoo, Jeong Sub Lim, Hyun Joon Shin, Ji Hong Kim, Do Hwan Kim   +8 more
wiley   +1 more source

12‐HETE Is an Endogenous Modulator of BLT2 Triggering Vascular Degeneration, Dissection, and Rupture

Advanced Science, EarlyView.
In thoracic aortic dissection (TAD), elevated levels of the arachidonic acid metabolite 12‐HETE, produced by macrophage‐specific 12/15‐lipoxygenase (12/15‐LOX), bind to the BLT2 receptor on vascular cells. This activates the NOX‐1/ROS/NF‐κB signaling pathway, leading to IL‐6 release.
Yuyu Li, Jiaqi Yu, Weiyao Chen, Xue Wang, Xin Tan, Jing Cui, Yihao Wang, Xuan Xu, Rui Lin, Zhengkai Wang, Wenxi Jiang, Yongliang Zhong, Jie Du, Yuan Wang   +13 more
wiley   +1 more source

Acute myocardial infarction secondary to direct myocardial infiltration by a malignant neoplasia [PDF]

, 2010
David Vivas, Borja Ruiz-Mateos, Eduardo Franco   +2 more
openalex   +1 more source

Reinstating Niche Failure in Diabetic Cranial Defects via Chronotaxic Signal‐Amplifying Fluidic Biomimetic Hydrogel

Advanced Science, EarlyView.
An in situ moldable GelSSO/PDA@SDF hydrogel functions as a chronotaxic signal‐amplifying biomimetic niche to restore regenerative failure in diabetic cranial defects. By sequentially releasing SDF‐1α‐loaded PDA nanoparticles and osteoinductive oligodeoxynucleotides, it orchestrates immunomodulation, progenitor recruitment, angiogenesis, and ...
Yingji Mao, Yu Chen, Runlin Fan, Pengzhen Zhuang, Hongbo Zhang, Pinghui Zhou   +5 more
wiley   +1 more source

Cardiac arrest and post-discharge mortality in patients with myocardial infarction: A large-scale nationwide registry analysis

Resuscitation Plus
Background: Cardiac arrest is a serious complication of acute myocardial infarction. The implementation of contemporary approaches to acute myocardial infarction management, including urgent revascularization procedures, has led to significant ...
Hirohiko Ando, Mitsuaki Sawano, Shun Kohsaka, Hideki Ishii, Atomu Tajima, Wataru Suzuki, Ayako Kunimura, Yusuke Nakano, Ken Kozuma, Tetsuya Amano   +9 more
doaj   +1 more source

P3662CRP predicts cap thickness in the culprit lesions of patients with metabolic syndrome and acute myocardial infarction. An Optical Coherence Study [PDF]

, 2017
Αndreas Synetos, Angelos Papanikolaou, Georgios Georgiopoulos, G. Peskesis, Maria Drakopoulou, Spyridon P. Galanakos, Αντώνιος Καρανάσος, Konstantinos Stathogiannis, I. Koutajiar, Kostas Toutouzas, Dimitris Tousoulis   +10 more
openalex   +1 more source

RELATIONSHIP BETWEEN PARAMETERS OF ADIPOKINE AND LIPID PROFILES IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND TYPE 2 DIABETES MELLITUS

, 2022
M. Yu. Koteliukh
openalex   +2 more sources

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

Advanced Science, EarlyView.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source