Results 61 to 70 of about 588,754 (299)

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Review of Atrioventricular Node Ablation Combined with Permanent His-Purkinje Conduction System Pacing in Patients with Atrial Fibrillation with Heart Failure

Reviews in Cardiovascular Medicine
With the advancement of pacing technologies, His-Purkinje conduction system pacing (HPCSP) has been increasingly recognized as superior to conventional right ventricular pacing (RVP) and biventricular pacing (BVP).
Lina Wang, Chen Tan, Jingshu Lei, CHONGYOU LEE   +3 more
doaj   +1 more source

Allopurinol use associated with increased risk of acute myocardial infarction in older people in a case–control study

Tzu Chi Medical Journal, 2019
Objective: There is controversy about the association between the allopurinol use and the risk of acute myocardial infarction. The aim of the study was to examine the association between allopurinol use and acute myocardial infarction in older people in
Kuan-Fu Liao, Cheng-Li Lin, Shih-Wei Lai   +2 more
doaj   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Acute myocardial infarction on Nongated chest computed tomography

Radiology Case Reports, 2020
Contrast-enhanced chest computed tomography (CT) is not considered part of the evaluation of myocardial infarction. However, acute myocardial infarction has been detected on contrast-enhanced chest CT as areas of decreased myocardial enhancement in ...
Maria Salgado Guerrero, MD, Gabriela Cepeda De Jesus, MD, Wakil Irfan, MD, Geraldine Villasana Gomez, MD, Ana B. Arevalo, MD, Robert Faillace, MD   +5 more
doaj   +1 more source

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

Advanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour, Daniel Cohn, Ishita Sarkar, Raja Alamore, Kareem Abd Rbo, Offer Amir, Dean Nachman   +6 more
wiley   +1 more source

Association between Serum Calcium and First Incident Acute Myocardial Infarction: A Cross-Sectional Study

Iranian Journal of Public Health, 2020
Background: The role of serum calcium in coronary artery disease (CAD) patients with or without first incident acute myocardial infarction has not been studied previously.
Chi ZHANG, Bangming CAO, Xingmei HUANG, Jian GU, Ming XIA, Xiangjun YANG, Hongxia LI   +6 more
doaj   +1 more source

Bivalirudin versus unfractionated heparin: a meta-analysis of patients receiving percutaneous coronary intervention for acute coronary syndromes [PDF]

, 2015
OBJECTIVE: Acute coronary syndrome (ACS) encompasses ST segment elevation myocardial infarction (STEMI), with generally high thrombus burden and non-ST segment elevation ACS (NSTE-ACS), with lower thrombus burden.
Farag, M, Gorog, DA, Prasad, A, Srinivasan, M   +3 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source