Results 91 to 100 of about 1,760,646 (211)

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3819-3830, November 2026.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

The Causal Link Between Air Pollution and Respiratory Diseases: Evidence from Granger Causality Test

Thoracic Research and Practice
OBJECTIVE: Air pollution can exacerbate respiratory illnesses, such as asthma, chronic obstructive pulmonary disease (COPD), pneumonia, bronchitis, and upper respiratory tract infections (URTIs).
Döndü Şanlıtürk
doaj   +1 more source

ПРИМЕНЕНИЕ МУКОАКТИВНЫХ ЛЕКАРСТВЕННЫХ СРЕДСТВ В ПРАКТИКЕ ТЕРАПЕВТА

Архивъ внутренней медицины, 2013
Russia is among the countries where using of mucolytic drugs in clinical practice is widespread. In chronic bronchitis, chronic obstructive pulmonary disease, acute respiratory syndrome with prolonged cough, pneumonia, tuberculosis and many other ...
Ф. Т. Малыхин, А. А. Визель, И. Ю. Визель   +2 more
doaj   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 4003-4016, November 2026.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

SPECIFIC CHARACTERISTICS AND TREATMENT OF ACUTE OBSTRUCTIVE BRONCHITIS IN CHILDREN OF EARLY AGE

, 2023
Obstructive, in this case, there is a blockage (obstruction) of the lumen of the bronchi with a large amount of mucus and sputum. Blockage of the bronchi is dangerous for the development of respiratory failure and oxygen starvation, which is especially dangerous in young children. The inflammatory process can spread from the trachea to the bronchus. In
openaire   +1 more source

Microfluidic Profiling of an Immune Cell‐Associated Extracellular Vesicle Signature for Active Tuberculosis Diagnosis and Treatment Monitoring

Journal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
Integrating microfluidic parallel detection with an innate immune extracellular vesicle signature enables rapid active tuberculosis diagnosis from 10 µL of plasma in 30 minutes, effectively discriminating non‐tuberculous respiratory diseases and monitoring treatment response.
Eun Ju Lee, Cheng Nie, Sunyoung Park, Yun‐Jeong Kang, Minji Kang, Jake Whang, Go‐Eun Choi, Hyejon Lee, San‐Nae Cho, Kyung‐A Hyun, Sunghyun Kim, Hyo‐Il Jung, Jungho Kim   +12 more
wiley   +1 more source

Peculiarities of lipids oxydation and асtіvіtу of superoxyddismutasae аt patients with chronic obstructive bronchitis

, 2002
lntensification of lipids peroxydation processes was revealed at patients with chronic obstructive bronchitis, which was associated bу depression of superoxyddismutasa antioxydant activity.
Решетар, О. І., Решетар, Д. В., Габор, М. Л., Лемко, Ольга Іванівна   +3 more
core  

Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease [PDF]

, 2006
Title: Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease. Purpose: This study examined the effects of a non-invasive ventilator on submaximal and maximal exercise performance in ...
Doggett, Anita
core   +2 more sources

High‐Throughput Geocoding to Assess Short‐Term Air Pollution in Correlation With Mortality in a French Cancer Patient Cohort

International Journal of Cancer, Volume 159, Issue 8, Page 2054-2065, 15 October 2026.
Although chronic air pollution exposure is linked to lung cancer mortality, the short‐term effects of fluctuating air quality on overall cancer mortality remain uncertain. Here, the authors applied geomatics and machine‐learning models to retrospectively examine possible associations between 31‐day pollution exposure and mortality in a French cancer ...
Loice Pokam, Joséphine Bocquet, Nadia Hégarat, Julie Perlbarg‐Samson, Thomas Balezeau, Maud Milder, Bastien Rance, Hector Countouris, Julien Guerin, Flavien Gilles, Jean Gaudart, Nicolas Girard, Clémence Basse   +12 more
wiley   +1 more source

The usage of modern radial diagnostic technologies in practical medicine

Бюллетень сибирской медицины, 2002
In the article the view of the scientific researches of the Department of radial diagnostic in SSMU is presented. Within the frames of the department interests besides the traditional researches in the fields of roentgenology there are such modern ...
V. D. Zavadovskaya
doaj   +1 more source