Results 221 to 230 of about 475,973 (337)

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Metabolic Signatures of Acinetobacter baumannii and Klebsiella pneumoniae Infections in Acute-on-chronic Liver Failure. [PDF]

Cell Mol Gastroenterol Hepatol
Cadoli C, Arif S, Ballhorn W, Brieger A, Brol MJ, Castelli F, Erasmus HP, Fischer J, Gurke R, Hahnefeld L, Junot C, Kraus N, Ortiz C, Schierwagen R, Torres SG, Uschner FE, Müller V, Trebicka J, Welsch C, Kempf VAJ.   +19 more
europepmc   +1 more source

Acute-on-Chronic Liver Failure: A Portuguese Single-Center Reference Review [PDF]

, 2017
Miguel Verdelho, Rui Perdigoto, João Machado, Élia Mateus, Paulo Marcelino, Rui Pereira, Philip Fortuna, Luís Bagulho, Luís Bento, Francisco Ribeiro, Fernando Nolasco, Américo Martins, Eduardo Barroso   +12 more
openalex   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Unique gut microbiota and metabolomic profiling as biomarker of post-transplant recovery in acute-on-chronic liver failure after liver transplantation. [PDF]

Appl Microbiol Biotechnol
Xiang X, Zhu J, Jiang J, Ding P, Zhu Y, Cheng K, Ming Y.   +6 more
europepmc   +1 more source

A case of liver calcification with chronic renal failure, after acute myocardial infarction.

, 1996
Tadashi Kuji, Kazuyoshi Takeda, Y. Watanabe, Yoichi Sumida, Shigeru Asahina, Yutaka Kitamura, Kikuhiko Higuma, Nobuyoshi Takagi   +7 more
openalex   +2 more sources

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Pediatric liver transplantation. Part II. Diagnostic imaging in postoperative management [PDF]

, 1985
Bron, KM, Cienfuegos, X, Dominguez, K, Gartner, JC, Ledesma-Medina, L, Starzl, TE, Young, LW   +6 more
core   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Association between serum albumin to creatinine ratio and mortality risk in patients with acute-on-chronic liver failure. [PDF]

Sci Rep
Xie J, Bian T, Su J, Xu S, Zhao L.
europepmc   +1 more source