Results 111 to 120 of about 40,513 (280)

Altered cytoskeletal integrity underlies impaired platelet shape change and defective thrombus formation in ETV6‐related thrombocytopenia

British Journal of Haematology, Volume 208, Issue 6, Page 1965-1979, June 2026.
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov, Julia‐Jessica D. Korobkin, Daria V. Fedorova, Sofia V. Galkina, Maria M. Golomysova, Sergei I. Obydennyi, Anastasia A. Ignatova, Ekaterina‐Iva A. Adamanskaya, Eugenia V. Yushkova, Anna V. Pavlova, Pavel A. Zharkov, Igor I. Kireev, Galina A. Novichkova, Viktor G. Zgoda, Mikhail A. Panteleev, Anastasia N. Sveshnikova   +15 more
wiley   +1 more source

Functional Data Strengthen Clinical Validation of PhenoScore Phenotype‐Guided AI for ANKRD11 Missense Variants

Clinical Genetics, Volume 109, Issue 6, Page 1038-1048, June 2026.
PhenoScore, an AI framework integrating facial recognition and clinical phenotype data, accurately identifies pathogenic ANKRD11 missense variants associated with KBG syndrome (AUC 0.95). Validated against functional data, PhenoScore outperforms REVEL and complements AlphaMissense, providing objective phenotypic evidence to reduce variants of uncertain
Evi Andriessen, Elke de Boer, Gholson J. Lyon, Bert B. A. de Vries, Charlotte W. Ockeloen, Alexander J. M. Dingemans   +5 more
wiley   +1 more source

Low Cord Blood Pneumococcal Immunoglobulin G (IgG) Antibodies Predict Early Onset Acute Otitis Media in Infancy [PDF]

, 1997
Juan Carlos Salazar, Kathleen Daly, G. Scott Giebink, Bruce R. Lindgren, Carol L. Liebeler, Mary H. Meland, Chinh T. Lé   +6 more
openalex   +1 more source

Acute Otitis Media and Facial Paralysis in Children: A Systemic Review and Proposal of an Operative Algorithm [PDF]

, 2023
Piergabriele Fichera, Luca Bruschini, Stefano Berrettini, Silvia Capobianco, Giacomo Fiacchini   +4 more
openalex   +1 more source

THE EFFECT OF GINGER EXTRACTS ON BACTERIAL ISOLATES FROM PATIENTS WITH SUPPURATIVE OTITIS MEDIA AND EXTERNA: IN VITRO STUDY

The Iraqi Journal of Medical Sciences, 2018
Background: Otitis media is a group of complex inflammatory disorders affecting the middle ear, which can be acute or chronic. Otitis externa is an inflammation on the skin of the external auditory canal usually associated with secondary ...
Maha Mohammed, Azhar Al-Attraqchi, Jaafer Al-Hasseni, Hayder Sahib   +3 more
doaj   +1 more source

Indications for antimicrobials in Acute otitis media [PDF]

, 2006
Acute otitis media is a condition affecting all age groups, particularly children, which commonly presents to the General Practitioner Although correctly diagnosed by the majority of doctors, otitis media is very commonly treated indiscriminately with ...
Gatt, Andre Stefan, Said, Mario E.
core  

Impact of Respiratory Viral Codetections on RSV Disease Burden in Young Children in Primary Care

Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.
ABSTRACT Background Young children with respiratory syncytial virus (RSV) often have viral coinfections. This study assessed the impact of respiratory viral codetections on RSV disease burden in children < 5 years and whether this varies by specific codetected viruses.
Levi Duijst, Valérie Sankatsing, Caterina Rizzo, Francesco Baglivo, Elizabeth Button, Marta Carballal Mariño, María Garcés Sánchez, Christine Hagemann, Simon de Lusignan, Oliver Martyn, Marc Raes, Daan Van Brusselen, Joanne Wildenbeest, Sarah Hak, Foekje Stelma, Jojanneke van Summeren, on behalf of the RSV ComNet network   +16 more
wiley   +1 more source

Antibiotics for acute otitis media in children.

, 2004
BACKGROUND: Acute otitis media is one of the most common diseases in early infancy and childhood. Antibiotic use for acute otitis media varies from 31% in the Netherlands to 98% in the USA and Australia.
Del Mar, Del, Chris B Del Mar, Sanders, SL, Del Mar, CB, Paul P Glasziou, Hayem, M, Maroeska M Rovers, Glasziou, PP, Sharon Sanders   +8 more
core   +1 more source

Clinical and behavioral determinants in pediatric non‐immediate drug hypersensitivity: Low confirmation but persistent avoidance

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
Abstract Background Non‐immediate drug hypersensitivity reactions (DHRs) in children are frequently overdiagnosed, leading to unnecessary drug avoidance. Evidence regarding predictors of more extensive reactions, drug provocation test (DPT) outcomes, and re‐exposure behavior and avoidance remains limited.
Ozge Can Bostan, Ozge Soyer, Marios Papadopoulos, Sophia Tsabouri   +3 more
wiley   +1 more source

187. Nasopharyngeal Testing to Individualize Management of Acute Otitis Media

, 2022
Thresia Sebastian, Mohammad Usama Toseef, Melanie Kurtz, Holly M. Frost   +3 more
openalex   +1 more source