Results 111 to 120 of about 5,370,990 (384)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

From acute to chronic pain after thoracic surgery: the significance of different components of the acute pain response

open access: yesJournal of Pain Research, 2018
Purpose Acute postoperative pain is a strong predictor for postthoracotomy pain syndrome (PTPS), but the mechanism is unknown. Even though thoracic pain is usually considered the dominating acute pain after thoracic surgery, up to 45% of patients ...
M. Blichfeldt-Eckhardt   +4 more
semanticscholar   +1 more source

Pregabalin effect on acute and chronic pain after cardiac surgery [PDF]

open access: yes, 2017
Introduction. Pain after cardiac surgery affects long-term patient wellness. This study investigated the effect of preoperative pregabalin on acute and chronic pain after elective cardiac surgery with median sternotomy. Methods.
Arnaoutoglou, Elena   +6 more
core   +3 more sources

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

open access: yesAdvanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez   +2 more
wiley   +1 more source

Dexmedetomidine in perioperative acute pain management: a non-opioid adjuvant analgesic

open access: yesJournal of Pain Research, 2017
Many nociceptive, inflammatory, and neuropathic pathways contribute to perioperative pain. Although opioids have long been a mainstay for perioperative analgesia, other non-opioid therapies, and dexmedetomidine, in particular, have been increasingly used
Chaoliang Tang, Z. Xia
semanticscholar   +1 more source

Non-specific abdominal pain and air pollution: a novel association. [PDF]

open access: yes, 2012
We studied whether short-term exposure to air pollution was associated with non-specific abdominal pain in epidemiologic and animal studies. Patients visiting the emergency department with non-specific abdominal pain were identified in Edmonton (1992 to
Fichna, Jakub   +8 more
core   +3 more sources

Long-Acting Morphine Following Hip or Knee Replacement: A Randomized, Double-Blind, Placebo-Controlled Trial

open access: yesPain Research and Management, 2012
BACKGROUND: Patients undergoing total hip or knee replacement surgery experience unmanaged pain during postoperative physiotherapy sessions. It was theorized that a baseline opioid would improve pain management.
Shirley L Musclow   +4 more
doaj   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht   +5 more
wiley   +1 more source

Classification of acute pain trajectory after breast cancer surgery identifies patients at risk for persistent pain: a prospective observational study

open access: yesJournal of Pain Research, 2018
Purpose Predictive value and accuracy of the acute pain trajectory were compared with those of pain intensity at 1 day after the surgery for pain prevalence at 6 months after the surgery.
A. Okamoto   +11 more
semanticscholar   +1 more source

Pain rewarded: hyperalgesic and allodynic effect of operant conditioning in healthy humans : protocol for a systematic review and meta-analysis [PDF]

open access: yes, 2018
Background: "pain rewarded" is a hypothesis wherein acute pain sufferers are exposed to reinforcers and punishers from their environment that shape their behaviour, i.e. pain responses.
Adamczyk, Wacław Marceli   +3 more
core   +1 more source

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