Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
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Development and Validation of an Owner-Assessed Feline Acute Pain Scale: Validation and Agreement with Veterinary Scales. [PDF]
Rojsiripornchai S +7 more
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The effect of low-dose ketamine compared to morphine on the severity of acute pain in emergency situations: a systematic review and meta-analysis. [PDF]
Zhang J, Ma B.
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Development and internal-external validation of a risk prediction model for acute pain after HAIC for patients with liver cancer using logistic regression and XGBoost algorithm. [PDF]
Cao J +7 more
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Acute pain trajectories in elderly patients with fragility hip fractures. [PDF]
Potnuru P +9 more
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Acute pain impairs retention of locomotor learning, regardless of the context of retention testing. [PDF]
Jackson SR, Pohlig RT, Morton SM.
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Acute Pain After Total Knee Arthroplasty: 2-Arachidonoylglycerol Tone and Endocannabinoid/Eicosanoid Crosstalk. [PDF]
Schutz L +11 more
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Postanaesthesia care units used to echo with cries of patients in pain after general anaesthesia. Each as-needed dose of analgesia was given only after permission of the surgeon or anaesthesiologist. Once conscious, patients were required to request each subsequent analgesic dose until hospital discharge.
D B, Carr, L C, Goudas
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