Results 61 to 70 of about 5,496,231 (361)
Pain Research and Management, 2017 In recent years, gabapentin has gained popularity as an adjuvant therapy for the treatment of postoperative pain. Numerous studies have shown a decrease in pain score, even with immediate postoperative activity, which is significant for early post-op ...
Jean Daniel Eloy +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Acute pain in surgical patients
, 2006 PURPOSE: The aim of this study was to assess experiences of acute surgical pain by patient description of pain intensity and patient satisfaction with peri-operative pain management in a variety of adult surgical patients prior to the appointment of an ...
Anthony Schoenwald +3 more
core +1 more source
The neurobiology of acute pain [PDF]
The Veterinary Journal, 2018 The mechanisms by which noxious stimuli produce the sensation of pain in animals are complex. Noxious stimuli are transduced at the periphery and transmitted to the CNS, where this information is subject to considerable modulation. Finally, the information is projected to the brain where it is perceived as pain.
openaire +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Corticofugal outputs facilitate acute, but inhibit chronic pain in rats [PDF]
, 2009 It has been widely accepted that the primary somatosensory cortex (SI) plays an essential role in the sensory-discriminative aspect of pain perception. However, it remains unclear whether the SI has a role in the descending modulation of pain.
Fei Luo +5 more
core +2 more sources
SAGE Open, 2018 This article describes outcomes of the complex therapy of Parkinson’s disease according to Operation and Procedure Code 8-97d, an interdisciplinary approach to the treatment of Morbus Parkinson established in Germany.
Tobias Romeyke +3 more
doaj +1 more source
Medical Cannabis and Cannabinoids, 2022 Multilocular pain syndromes with advanced chronification lead to a significant reduction in the quality of life of patients. The administration of cannabis is currently being discussed in the context of therapy-resistant pain and increasing opiate abuse.
Tobias Romeyke, Rudolf Westfal
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Global Advances in Health and Medicine, 2018 Objectives The aim of this article is to study patient satisfaction with complementary and alternative medicine (CAM) in an in-hospital setting before and after the introduction of diagnosis-related groups (DRGs).
Tobias Romeyke PhD +3 more
doaj +1 more source