Results 111 to 120 of about 107,794 (297)
Disrupted endocannabinoid signaling contributes to systemic inflammation in acute pancreatitis
The Journal of Pathology, EarlyView.Abstract Acute pancreatitis (AP) is an inflammatory disease that can lead to systemic complications in severe cases. The endocannabinoid system has emerged as a potential modulator of inflammation in AP. We investigated the role of the endocannabinoid 2‐arachidonoylglycerol (2‐AG) and the cannabinoid receptors CB1 and CB2 during AP.
Paula Goncalves‐Romeu +7 more
wiley +1 more source
Sickle Cell Disease: Historical Overview and Current Therapies
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde +4 more
wiley +1 more source
Lipid levels and risk of acute pancreatitis using bidirectional Mendelian randomization
Scientific ReportsPrevious studies found lipid levels, especially triglycerides (TG), are associated with acute pancreatitis, but their causalities and bi-directions were not fully examined. We determined whether abnormal levels of TG, high-density lipoprotein cholesterol
Biqi Wang +8 more
doaj +1 more source
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Portal Hypertension &Cirrhosis, EarlyView.Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble
Portal Hypertension &Cirrhosis, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen +5 more
wiley +1 more source
The Recent Pharmacological Approaches to the Acute Pancreatitis
, 2018 There are several treatments for the acute pancreatitis. The pharmacological therapies have important role in the pain control, the decreasing the incidence rate of the infectious complications, and the reducing exocrine stimulation.
Kim, Yosub
core
Environmental Toxicology, EarlyView.ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley +1 more source
Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies
BiomoleculesAcute pancreatitis remains a serious public health problem, and the burden of acute pancreatitis is increasing. With significant morbidity and serious complications, appropriate and effective therapies are critical.
Wenkai Jiang +3 more
doaj +1 more source
Role of endoscopic ultrasonography in the diagnostic work-up of idiopathic acute pancreatitis (PICUS): study protocol for a nationwide prospective cohort study [PDF]
, 2020 INTRODUCTION: Idiopathic acute pancreatitis (IAP) remains a dilemma for physicians as it is uncertain whether patients with IAP may actually have an occult aetiology.
Dutch Pancreatitis Study Group
core
Veterinary Record, Volume 196, Issue 6, 15/22 March 2025.Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli +3 more
wiley +1 more source