Results 141 to 150 of about 211,431 (346)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Acute pancreatitis: current perspectives on diagnosis and management

open access: yesJournal of Inflammation Research, 2018
Adarsh P Shah, Moustafa M Mourad, Simon R Bramhall Department of Surgery, Hereford County Hospital, Hereford, UK Abstract: The last two decades have seen the emergence of significant evidence that has altered certain aspects of the management ...
Shah AP, Mourad MM, Bramhall SR
doaj  

Institutional Outcomes following Total Pancreatectomy and Islet Autotransplantation in Children [PDF]

open access: yes, 2018
Purpose: Total pancreatectomy with islet autotransplantation (TPIAT) is used to treat debilitating chronic pancreatitis (CP) and acute recurrent pancreatitis (ARP) that has failed medical and endoscopic therapy.
Sekoulopoulos, Stephen P
core   +1 more source

Role of Bile Acids and Bile Salts in Acute Pancreatitis

open access: hybrid, 2020
Quang Trung Tran   +13 more
openalex   +1 more source

THE M-RNA, EXPRESSION OF SERCA2 AND NCX1 IN THE PROCESS OF PHARMACOLOGICAL CELL PROTECTION IN EXPERIMENTAL ACUTE PANCREATITIS INDUCED BY TAUROCHOLATE

open access: gold, 2022
Ênio R. Vasques   +9 more
openalex   +1 more source

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