Results 221 to 230 of about 107,794 (297)

Semaglutide 2.4 mg Cardiometabolic Long‐Term Effects in Patients With Obesity or Overweight in a Real‐World Setting: A Retrospective Cohort Study in the United States (SMILE)

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 6121-6130, July 2026.
ABSTRACT Aims To evaluate the real‐world associations between semaglutide 2.4 mg and cardiometabolic comorbidities, biomarkers and cardiovascular risk among adults with overweight or obesity. Methods This retrospective cohort study used US claims data and laboratory measurements from the Komodo Research Database (2016–2024). Adults with obesity or with
Aleksandrina Ruseva, Wojciech Michalak, Matthew Bassan, Ella Xiaoyan Du, Anthony Fabricatore, Bríain Ó Hartaigh, Theo Man, Ramya Ramasubramanian, Pangsibo Shen, Jinlin Song, Zhenxiang Zhao, Francisco Lopez‐Jimenez   +11 more
wiley   +1 more source

Ph‐Negative Acute Lymphoblastic Leukemia in the Older Adults: Biology, Therapeutic Strategies and Unmet Needs

European Journal of Haematology, Volume 117, Issue 1, Page 24-41, July 2026.
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Marco Fiorillo, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

STATs Signaling Pathways in Acute Pancreatitis: Mechanisms and Regulation. [PDF]

Int J Med Sci
Peng Y, Lin AE, Yang FN, Tang YM, Yao JQ, Tang Y, Miao YF.   +6 more
europepmc   +1 more source

Liver Injury From Medications Used for Treating Inflammatory Bowel Disease: The Drug‐Induced Liver Injury Network Experience

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background We aimed to investigate and characterise DILI due to approved therapies for inflammatory bowel disease (IBD). Methods Using the Drug‐Induced Liver Injury Network (DILIN) prospective study, we evaluated definite, highly likely, or probable DILI attributed to IBD therapies, including use for non‐IBD indications (but excluding ...
Harish Gopalakrishna, Jiezhun Gu, Yi‐Ju Li, Huiman Barnhart, Dina Halegoua‐DeMarzio, Herbert L. Bonkovsky, A. Sidney Barritt, Jean P. Molleston, Naga P. Chalasani, Marwan Ghabril   +9 more
wiley   +1 more source

Survey on Inter‐ and Intra‐Observer Variations of the Ultrasound Assessment of Dog Pancreases

Veterinary Radiology &Ultrasound, Volume 67, Issue 4, July 2026.
ABSTRACT Abdominal ultrasonography (AUS) is considered an important diagnostic tool for assessing pancreatic disease in dogs. However, AUS interpretation is highly subjective and operator‐dependent, with no prior studies evaluating observer variability in assessing the canine pancreas.
R. B. S. Turner, S. M. Firestone, F. R. Dunshea, C. Mansfield   +3 more
wiley   +1 more source

A time-series feature-based nomogram for the prediction of severe acute pancreatitis. [PDF]

BMC Gastroenterol
Chen Y, Fu Z, Liu Y, Jiang F, Zhu T, Jiang L.   +5 more
europepmc   +1 more source

The Predictive Accuracy of Methods Commonly Used for Evaluating Animal Distress

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Predictive accuracy of body weight change, distress score, burrowing, and nesting behavior across multiple intervention phases. ABSTRACT Accurate distress assessment is essential for ensuring animal welfare and scientific validity. Although behavioral and physiological indicators are commonly used, their predictive value across disease models and ...
Emily Leitner, Annika Thämlitz, Muhammad Imran Khan, Benjamin Schulz, Simone Kumstel, Brigitte Vollmar, Dietmar Zechner   +6 more
wiley   +1 more source

Has the Step-Up Approach Improved Prognosis in Severe Necrotizing Acute Pancreatitis? [PDF]

J Clin Med
Gadea-Mateo R, Garcés-Albir M, Dorcaratto D, Kadzhaya-Khlystov G, Sanchiz V, Muñoz-Forner E, Villagrasa R, Mora-Oliver I, Casula E, Juan-Diaz M, Navarro-Cortés P, Guijarro-Rosaleny J, Pascual-Moreno I, Sabater L.   +13 more
europepmc   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack, Wan‐Chun Chang, Miguel Cordova‐Delgado, Spencer J. Anderson, Jessica N. Trueman, Erika N. Scott, Catrina M. Loucks, Shahrad R. Rassekh, Gabriella S. S. Groeneweg, Michelle Higginson, Kathy Li, Fudan Miao, Derek Yau, Donna Johnston, Mounira Ibrahim, Maja Krajinovic, Thai Hoa Tran, Jessica Tewfik, Jean‐François Bussières, Thaïna‐Rafi Jean‐Baptiste, Denis Lebel, Lucie Pecheux, Bina Gyawali, Gregory Guilcher, Gesche Riabowol, Geert ’t Jong, Michelle Staub, Geoff Cuvelier, Kathleen Felton, Sara Khalaj, Michael Rieder, Awatif Abuzgaia, Tamorah Lewis, Himal Ghimire, Paul Nathan, Kerry Goralski, Ketan Kulkarni, Zara Forbrigger, Colin J. D. Ross, Bruce C. Carleton   +39 more
wiley   +1 more source

The Role of Macrophages in Acute Pancreatitis: From Inflammatory Drivers to Therapeutic Targets. [PDF]

Int J Med Sci
Xu Z, Sui YC, Sheng LP.
europepmc   +1 more source