Results 31 to 40 of about 88,247 (249)

Pancreatic duct patterns in acute pancreatitis: a MRI study. [PDF]

PLoS ONE, 2013
OBJECTIVES: To study the MRI findings of the pancreatic duct in patients with acute pancreatitis. MATERIALS AND METHODS: A total of 239 patients with acute pancreatitis and 125 controls were analyzed in this study.
Rong Peng, Xiao Ming Zhang, Yi Fan Ji, Tian Wu Chen, Lin Yang, Xiao Hua Huang, Xiao Xiao Chi   +6 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Risk of acute atherosclerotic cardiovascular disease in patients with acute and chronic pancreatitis

Scientific Reports, 2021
The association between pancreatitis and acute myocardial infarction or stroke remains incompletely understood. This study aimed to evaluate the long-term risk of acute atherosclerotic cardiovascular disease (ASCVD) in people with acute and chronic ...
Li-Chin Sung, Chuen-Chau Chang, Chao-Shun Lin, Chun-Chieh Yeh, Yih-Giun Cherng, Ta-Liang Chen, Chien-Chang Liao   +6 more
doaj   +1 more source

A Pancreatitis‐Inspired Trypsinogen Nanoplatform Reprograms Tumor‐Associated Macrophages via NF‐κB for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
Trypsinogen‐loaded nanoparticles reprogram TAMs via NF‐κB/NLRP3, driving M2→M1 conversion and potent phagocytosis to unleash antitumor immunity. ABSTRACT Although reprogramming tumor‐associated macrophages (TAMs) represents a promising therapeutic strategy, approaches that are both precise and safe remain scarce.
Lei Cao, Yu He, Wenhao Li, Bo Gong, Han Lin, Jianlin Shi, Yuan Yong, Wencheng Wu   +7 more
wiley   +1 more source

High ANO1 expression is a prognostic factor and correlated with an immunosuppressive tumor microenvironment in pancreatic cancer

Frontiers in Immunology
BackgroundAminooctylamine (ANO1) plays an oncogenic role in various cancers. However. its role in pancreatic cancer (PC) has rarely been studied. This study investigated the prognostic value of ANO1 and its correlation with the tumor microenvironment ...
Guangnian Zhang, Zhihui Shu, Jun Yu, Jianshui Li, Pengsheng Yi, Bin Wu, Dawei Deng, Shu Yan, Yong Li, Dongmei Ren, Yifu Hou, Yifu Hou, Chuan Lan   +12 more
doaj   +1 more source

Evaluation of Acute Pancreatitis Patients: Single Center Five Years’ Experience

Journal of Contemporary Medicine, 2021
Aim: In the present study, the purpose was to examine the clinical and laboratory characteristics of patients diagnosed with Acute Pancreatitis in a third-line Children’s Emergency Department, and to draw attention to the importance of Acute Pancreatitis
Özlem Tolu Kendir, Hayri Yılmaz, Gokhan Tumgor, Sinem Sarı Gökay, Mehmet Ağın   +4 more
doaj   +1 more source

Pancreatic Atrophy: A Narrative Review and Surgical Interpretation

Annals of Gastroenterological Surgery, EarlyView.
Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino, Ken‐ichi Okada, Yohei Masugi, Eisuke Iwasaki, Masaki Mori   +4 more
wiley   +1 more source

Clinical characteristics and prognosis of older adult patients with necrotizing pancreatitis: a single center retrospective study

Journal of Pancreatology
Background:. Acute pancreatitis (AP) is a common condition encountered during clinical practice; 20% of patients have pancreatic necrosis, and the mortality is high.
Yue Wu, JiongDi Lu, Feng Cao, Fei Li
doaj   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

Animal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji, Maedeh Faraji, Nasrin Kazemipour   +2 more
wiley   +1 more source

Refining a preclinical model of viral myocarditis in accordance with biotech standards

Animal Models and Experimental Medicine, EarlyView.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen, Julia Riedesel, Juliane Stein, Brandon H. Greene, Svenja Rohde, Sonja Suess, Bjoern Keiner, Priya Panjwani, Padmapriya Ponnuswamy, Juan E. Camacho Londoño   +9 more
wiley   +1 more source