Results 31 to 40 of about 211,518 (344)

Pancreatic phospholipase A2 activity in acute pancreatitis: A prognostic marker for early identification of patients at risk [PDF]

, 2002
Remarkably elevated levels of phospholipase A(2) (PLA(2)) are measurable in human blood samples in cases of acute pancreatitis. The source of the enzyme was first thought to be exclusively the pancreas, but now it is generally accepted that two ...
Aufenanger, Johannes, Bertsch, Thomas, Fassbender, Klaus, Quintel, Michael, Samman, Michael, Zimmer, Wilma   +5 more
core   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Pathophysiology of acute experimental pancreatitis: Lessons from genetically engineered animal models and new molecular approaches [PDF]

, 2005
The incidence of acute pancreatitis is growing and worldwide population-based studies report a doubling or tripling since the 1970s. 25% of acute pancreatitis are severe and associated with histological changes of necrotizing pancreatitis. There is still
Anne Barbara Tietz, Arnush M, Bhagat L, Bhatia M, Bhatia M, Bockman DE, Burkhard Göke, Claus Schäfer, Demols A, Ebert MP, Frossard JL, Gardner JD, Gerard C, Grady T, Grisham M, Gu D, Gukovskaya AS, Gukovsky I, Hahm KB, Halangk W, Halangk W, Korc M, Lee MS, Leser HG, Massague J, Meda P, Norman J, Ohnishi H, Ohnishi H, Ohnishi H, Roberts AB, Saluja A, Schafer C, Schafer C, Schmid RM, Song AM, Steinle A, Van Acker GJD, Vogelmann R   +38 more
core   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Intracapillary leucocyte accumulation as a novel antihaemorrhagic mechanism in acute pancreatitis in mice [PDF]

, 2009
Background: Pancreatic infiltration by leucocytes represents a hallmark in acute pancreatitis. Although leucocytes play an active role in the pathophysiology of this disease, the relation between leucocyte activation, microvascular injury and haemorrhage
Deduchovas, O., Hartwig, W., Kerkadze, V., Märten, A., Parseliunas, A., Ryschich, E., Salnikova, O., Schmidt, J., Sperandio, Markus   +8 more
core   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

Readmission in acute pancreatitis: Etiology, risk factors, and opportunities for improvement

Surgery Open Science, 2022
Acute pancreatitis is associated with a readmission rate ranging from 7 to 34%. Readmission rates are highest among biliary (4–37%) and alcohol-induced (2–60%) acute pancreatitis.
Brittany D. Bogan, Sean P. McGuire, Thomas K. Maatman   +2 more
doaj   +1 more source

Formation of Pancreatoduodenal Fistula in Intraductal Papillary Mucinous Neoplasm of the Pancreas Decreased the Frequency of Recurrent Pancreatitis [PDF]

, 2019
Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are characterized by proliferation of mucin-secreting cells in the main pancreatic duct (PD) or its branches. The secreted thick mucin usually leads to PD obstruction and dilation.
Alkaade, Samer, Hammami, Muhammad B., Khneizer, Gebran, Reddy, Kavya M.   +3 more
core   +1 more source

Evaluation of Canine Pancreas-Specific Lipase Activity, Lipase Activity, and Trypsin-Like Immunoreactivity in an Experimental Model of Acute Kidney Injury in Dogs. [PDF]

, 2015
BackgroundDiagnosis of pancreatitis in dogs is complicated by extrapancreatic disorders that can alter the results of laboratory tests. Extrapancreatic disorders can also affect the diagnosis of exocrine pancreatic insufficiency (EPI).
Cowgill, LD, Hulsebosch, SE, Kass, PH, Marks, SL, Palm, CA, Segev, G   +5 more
core   +1 more source

Number of recurrences is significantly associated with the post-acute pancreatitis diabetes mellitus in a population with hypertriglyceridemic acute pancreatitis

Lipids in Health and Disease, 2023
Background Twenty-three percent of patients are diagnosed with diabetes mellitus after the first episode of acute pancreatitis. The incidence of post-acute pancreatitis diabetes mellitus is significantly higher than that of type 1 diabetes mellitus. Some
Xiamin Tu, Qingxie Liu, Lin Chen, Jie Li, Xiaoping Yu, Xiuping Jiao, Ningzhi Wang, Lianghao Hu, Yuan Yuan, Weijuan Gong, Yanbing Ding, Xiaolei Shi, Weiming Xiao, Guotao Lu   +13 more
doaj   +1 more source