Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley +1 more source
European Works Councils and the healthcare sector [PDF]
Profiles of healthcare companies with European Works Councils and some eligible ...
Lethbridge, Jane
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Exp erimental research of wearable artificial kidney
Aim. The article presents the results of wearable artificial kidney (WAK) biomedical trial based on peritoneal dialysis with continuous dialysate regeneration.Materials and methods. The trial was carried out on a 15-kg dog.
N. A. Bazaev +7 more
doaj +1 more source
Acute peritoneal dialysis is an efficient and reliable alternative therapy in preterm neonates with acute kidney injury. [PDF]
Xing Y +8 more
europepmc +1 more source
Acute Peritoneal Dialysis During the COVID-19 Pandemic at Bellevue Hospital in New York City [PDF]
Caplin NJ +18 more
europepmc +2 more sources
Direct healthcare costs of diabetes mellitus patients in Spain [PDF]
Objectives. To estimate the healthcare resources spent by diabetic patients in Spain during the year 2002. Methods. The present work is a cost-of-illness study.
Lobo, Félix +3 more
core +3 more sources
A Comprehensive Review on Effects of Peritoneal Dialysis in the Treatment of Acute Renal Damage [PDF]
Aim and objective: To evaluate the prevalence and impact of physical symptoms in peritoneal dialysis (PD) patients, assess the effectiveness of PD in managing acute kidney injury (AKI) during COVID-19 and in patients who are suffering from congestive ...
Sanjana Bhagat, Shubham Tiwari
doaj +1 more source
Acute peritoneal dialysis in COVID-19 [PDF]
Watanyu Parapiboon +2 more
openaire +2 more sources
Reversal of acute renal injury after peritoneal dialysis in a dog
. Guiot E.G., Guimarães-Okamoto P.T.C., Chacar F.C., Gomide P., Lourenço M.L.G. & Melchert A. [Reversal of acute renal injury after peritoneal dialysis in a dog.] Reversão da injúria renal aguda após diálise peritoneal em cão.
Êmille Gedoz Guiot +5 more
doaj
Accidental Potassium Bromate Poisoning Causing Acute Renal Failure [PDF]
Accidental poisoning is common in children. Potassium bromate is commonly used additive and raising agent in many edibles especially bread which is a staple food in Nigeria.
Adeleke, SI, Asani, MO
core

