Results 61 to 70 of about 35,850 (249)

Differences in SpeB protease activity among group A streptococci associated with superficial, invasive, and autoimmune disease. [PDF]

PLoS ONE, 2017
The secreted cysteine proteinase SpeB is an important virulence factor of group A streptococci (GAS), whereby SpeB activity varies widely among strains. To establish the degree to which SpeB activity correlates with disease, GAS organisms were recovered ...
Anhphan T Ly, John P Noto, Odaelys L Walwyn, Robert R Tanz, Stanford T Shulman, William Kabat, Debra E Bessen   +6 more
doaj   +1 more source

A 45-year-old Female with an Atypical Presentation of Pharyngitis [PDF]

, 2020
Introduction: Emergency physicians are trained to treat a variety of ailments in the emergency department (ED), some of which are emergent, while others are not. A common complaint seen in the ED is a sore throat.
Carney, Michael B., Glickman, Andrew A., Rodgers, Brian, Schander, Artur, Weber, Nancy   +4 more
core  

Phase 1/2 Study of Crizotinib in Children With Relapsed/Refractory ALK‐Positive Anaplastic Large Cell Lymphoma or Neuroblastoma in Japan

Cancer Science, EarlyView.
The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori, Akiko Kada, Tomoo Osumi, Daisuke Tomizawa, Yuhki Koga, Reiji Fukano, Kengo Takeuchi, Ukihide Tateishi, Osamu Miyazaki, Ryuta Asada, Akiko M. Saito, Kei Fukuhara, Masahiro Sekimizu   +12 more
wiley   +1 more source

Comparative Study Between Integrated Management of Childhood Illness Guidelines and Traditional Methods in Management of Acute Pharyngitis among Children Under Five Years in Zagazig District, Egypt

Journal of High Institute of Public Health, 2018
Background: Pharyngitis is one of the most frequently faced pediatric problems with serious complications in primary care. Objective(s): To compare between Integrated Management of Childhood Illness (IMCI) guidelines and traditional management ...
Abdalla H. M. Elsharkawy, Ghada M. Salem, Amel E. Mohamed, Maha S. Eltwansy   +3 more
doaj   +1 more source

Evaluation of uncomplicated acute respiratory tract infection management in veterans: A national utilization review. [PDF]

, 2019
BackgroundAntibiotics are overprescribed for acute respiratory tract infections (ARIs). Guidelines provide criteria to determine which patients should receive antibiotics.
ARI Management Improvement Group, Bidwell Goetz, Matthew, Bohan, Jefferson G, Burk, Muriel, Cunningham, Francesca, Jones, Makoto, Madaras-Kelly, Karl, Neuhauser, Melinda M, Pontefract, Benjamin   +8 more
core  

ING116070: a study of the pharmacokinetics and antiviral activity of dolutegravir in cerebrospinal fluid in HIV-1-infected, antiretroviral therapy-naive subjects. [PDF]

, 2014
BackgroundDolutegravir (DTG), a once-daily, human immunodeficiency virus type 1 (HIV-1) integrase inhibitor, was evaluated for distribution and antiviral activity in cerebrospinal fluid (CSF).MethodsING116070 is an ongoing, single-arm, open-label ...
Chen, Shuguang, extended ING116070 study team, Letendre, Scott L, Mills, Anthony M, Min, Sherene S, Piscitelli, Stephen C, Song, Ivy H, Tashima, Karen T, Thomas, Deborah A   +8 more
core   +6 more sources

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source

Prevalence of Microorganisms in Acute Pharyngitis from Throat Swab in a tertiary care hospital [PDF]

, 2021
Mumtaz Ahmad Umar, Mirza N. Baig, Nighat Arif, Naveed Arshad, Ayesha Jawad, Mahnoor Fatima   +5 more
openalex   +1 more source

Tracheal collapse rates in Kenyan working cart and pack donkeys

Equine Veterinary Journal, EarlyView.
Abstract Background Donkeys (Equus asinus) in East Africa are recognised as working with poorly designed harnesses and carts. The donkey cart used in regions of Africa, specifically Meru County, Kenya, appears to place the cart's weight solely on the donkey's mid‐cervical region.
Martha Mellish, Jennifer Burns, Yvonne Elce, Jason W. Stull   +3 more
wiley   +1 more source

Gonorrhea Management in High‐, Limited‐ and No‐Resource Settings: Implications in the Context of Antimicrobial Resistance

International Journal of Dermatology, EarlyView.
ABSTRACT Gonorrhea, a common sexually transmitted infection caused by Neisseria gonorrhoeae, represents an escalating global public health threat due to antimicrobial resistance. The current review explores diverse approaches around the globe to gonorrhea management across various settings, with a focus on diagnostic strategies, treatment practices ...
Andrei Tanasov, Maciej Pastuszczak, George‐Sorin Tiplica   +2 more
wiley   +1 more source