Results 61 to 70 of about 35,440 (255)

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

ING116070: a study of the pharmacokinetics and antiviral activity of dolutegravir in cerebrospinal fluid in HIV-1-infected, antiretroviral therapy-naive subjects. [PDF]

, 2014
BackgroundDolutegravir (DTG), a once-daily, human immunodeficiency virus type 1 (HIV-1) integrase inhibitor, was evaluated for distribution and antiviral activity in cerebrospinal fluid (CSF).MethodsING116070 is an ongoing, single-arm, open-label ...
Chen, Shuguang, extended ING116070 study team, Letendre, Scott L, Mills, Anthony M, Min, Sherene S, Piscitelli, Stephen C, Song, Ivy H, Tashima, Karen T, Thomas, Deborah A   +8 more
core   +6 more sources

Differences in SpeB protease activity among group A streptococci associated with superficial, invasive, and autoimmune disease. [PDF]

PLoS ONE, 2017
The secreted cysteine proteinase SpeB is an important virulence factor of group A streptococci (GAS), whereby SpeB activity varies widely among strains. To establish the degree to which SpeB activity correlates with disease, GAS organisms were recovered ...
Anhphan T Ly, John P Noto, Odaelys L Walwyn, Robert R Tanz, Stanford T Shulman, William Kabat, Debra E Bessen   +6 more
doaj   +1 more source

Visit complexity, diagnostic uncertainty, and antibiotic prescribing for acute cough in primary care: a retrospective study [PDF]

, 2014
Background: Guidelines and performance measures recommend avoiding antibiotics for acute cough/acute bronchitis and presume visits are straightforward with simple diagnostic decision-making.
Businger, Alexandra C, Dempsey, Patrick P, Linder, Jeffrey A, Whaley, Lauren E   +3 more
core   +1 more source

Point‐Of‐Care Respiratory Diagnosis and Antibiotic Utilization in the Emergency Department: A Prospective Evaluation of Multiplex PCR

Academic Emergency Medicine, EarlyView.
ABSTRACT Objectives Rapid multiplex point‐of‐care (POC) PCR tests may reduce unnecessary antibiotic prescribing by quickly identifying viral etiologies in patients with acute respiratory infections (ARI). We evaluated the impact of a rapid (~15 min) multiplex PCR test on antibiotic prescribing, provider confidence, patient satisfaction, and emergency ...
Andrew C. Meltzer, Christopher Payette, Ryan Heidish, Isabella Lagunzad, Aditya Loganathan, Taylor Bolden, Michael Friedman, Matteo Pieri, William Huang, Dominic DeBritz, Nora Luck, Sean M. Lee   +11 more
wiley   +1 more source

Comparative Study Between Integrated Management of Childhood Illness Guidelines and Traditional Methods in Management of Acute Pharyngitis among Children Under Five Years in Zagazig District, Egypt

Journal of High Institute of Public Health, 2018
Background: Pharyngitis is one of the most frequently faced pediatric problems with serious complications in primary care. Objective(s): To compare between Integrated Management of Childhood Illness (IMCI) guidelines and traditional management ...
Abdalla H. M. Elsharkawy, Ghada M. Salem, Amel E. Mohamed, Maha S. Eltwansy   +3 more
doaj   +1 more source

Evaluation of uncomplicated acute respiratory tract infection management in veterans: A national utilization review. [PDF]

, 2019
BackgroundAntibiotics are overprescribed for acute respiratory tract infections (ARIs). Guidelines provide criteria to determine which patients should receive antibiotics.
ARI Management Improvement Group, Bidwell Goetz, Matthew, Bohan, Jefferson G, Burk, Muriel, Cunningham, Francesca, Jones, Makoto, Madaras-Kelly, Karl, Neuhauser, Melinda M, Pontefract, Benjamin   +8 more
core  

A Longitudinal Assessment of Endometriosis Patients Prescribed Cannabis‐Based Medicinal Products: A Case Series From the UK Medical Cannabis Registry

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Although there is growing evidence supporting the use of cannabis‐based medicinal products (CBMPs) for the management of chronic pain, there is a paucity of data on their effect on endometriosis‐associated chronic pain. Aims This study aimed to perform an analysis of pain‐specific and general health‐related quality of life (HRQoL ...
Sara Getter, Simon Erridge, John Warner‐Levy, Evonne Clarke, Katy McLachlan, Ross Coomber, Shelley Barnes, Alia Darweish Medniuk, Rahul Guru, Wendy Holden, Mohammed Sajad, Robert Searle, Azfer Usmani, Sanjay Varma, James J. Rucker, Michael Platt, Mikael H. Sodergren   +16 more
wiley   +1 more source

A feasibility service evaluation of screening and treatment of group A streptococcal pharyngitis in community pharmacies [PDF]

, 2016
Objectives The UK 5 year antimicrobial resistance strategy recognizes the role of point-of-care diagnostics to identify where antimicrobials are required, as well as to assess the appropriateness of the diagnosis and treatment.
A. P. R. Wilson, G. Marshall, Klepser, Lawrence, P. Howard, T. Thornley, Worrall   +6 more
core   +3 more sources

Open-Label Taste-Testing Study to Evaluate the Acceptability of Both Strawberry-Flavored and Orange-Flavored Amylmetacresol/2,4-Dichlorobenzyl Alcohol Throat Lozenges in Healthy Children [PDF]

, 2013
BACKGROUND: Acute sore throat (pharyngitis) is one of the most common illnesses for which children are seen by primary care physicians. Most cases are caused by viruses and are benign and self-limiting. Clinically proven, over-the-counter throat lozenges
Adrian Shephard, Alex Thompson, Emma Field, Sandie Reader   +3 more
core   +1 more source