Results 191 to 200 of about 75,739 (240)

Clinical and demographic characteristics of adolescents, emerging adults, and young adults presenting to an emergency department following a suicide attempt

open access: yesJCPP Advances, EarlyView.
Abstract Introduction Suicide is a significant public health concern and the second leading cause of death in adolescents and young adults. This study sought to better understand differences in demographic and clinical characteristics of young people who attempted suicide during three phases of this developmental period: late adolescence (14–17 years),
Nicholas M. Brdar   +7 more
wiley   +1 more source

Things We Do for No Reason™: Prescribing gabapentinoids for pain

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel   +4 more
wiley   +1 more source

Can trigeminal sensations impact saltiness perception? A mini‐review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan   +2 more
wiley   +1 more source

Quantitative Analysis of Locus Coeruleus Neurons and Thalamic Noradrenergic Axons in a Progressive 1‐Methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine Monkey Model of Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson's disease is mainly characterized by dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) and α‐synuclein accumulation. The locus coeruleus (LC) is also affected in Parkinson's disease and linked to some nonmotor symptoms, but the extent and timing of its degeneration remain unclear.
Megan Carrillo   +6 more
wiley   +1 more source

Re‐conceptualizing Parkinson's disease as a lifelong neurobiological trajectory: A framework for prevention

open access: yesNeuroprotection, EarlyView.
Three‐panel graphical abstract showing the Lifelong Neurobiological Trajectory framework for Parkinson's disease: (1) Vulnerability pathway (top, red) showing how early adversity → epigenetic dysregulation, neuroinflammation, and mitochondrial dysfunction → ↑ PD risk; (2) Lifespan timeline (middle, purple) spanning prenatal/infancy → childhood ...
Ayodeji Johnson Ajibare   +2 more
wiley   +1 more source

Rediscovery of Passiflora clypeophylla (subgenus Decaloba): a highly threatened and narrow endemic species found within a karstic canyon in Guatemala

open access: yesNordic Journal of Botany, EarlyView.
Passiflora clypeophylla, an endemic species to the Guatemalan karstic forests last seen in 1889 and deemed extinct, was rediscovered in the Department of Alta Verapaz, east of Cobán. The species was known only from a single specimen hailed from the type locality, Rubel Cruz, where it has been found again. An additional location has been identified in a
J.R. Kuethe   +3 more
wiley   +1 more source

Primula himalayana sp. nov., a new species from eastern Himalaya, India

open access: yesNordic Journal of Botany, EarlyView.
Primula himalayana sp. nov., a new species of Primulaceae, is described and illustrated from Tawang, Lutrem, 4238 m a.s.l., Arunachal Pradesh, India. It grows under Juniperus and Berberis scrub forest in an alpine meadow. The new species belong in Primula section Cordifoliae and is resembling P.
Bipankar Hajong   +2 more
wiley   +1 more source

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