Results 211 to 220 of about 618,791 (342)

Design, Synthesis, and Biological Characterization of Macromolecular Ester Prodrugs of a Selective Cyclooxygenase‐2 Inhibitor

open access: yesChemMedChem, EarlyView.
Two macromolecular ester prodrugs of a COX‐2 inhibitor are designed and synthesized. They are based on two different oligo(ethylene glycol) spacers linking the COX‐2 inhibitor to hyaluronic acid. The spacers are designed to differ in the sensitivity to the hydrolytic conditions.
Mario Saletti   +13 more
wiley   +1 more source

Epilepsy surgery: From bench to the clinics

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Strategy for effective analgesia with intravenous buprenorphine in patients with acute postoperative pain. [PDF]

open access: yesBMC Anesthesiol
Szczupak M   +5 more
europepmc   +1 more source

Geranium Essential Oil Use for Human Health: A Systematic Review of Clinical Evidence

open access: yesFlavour and Fragrance Journal, EarlyView.
Geranium essential oil (Pelargonium graveolens) demonstrates efficacy in alleviating anxiety, pain and dermatological conditions, supporting its use as a safe, low‐cost complementary therapy. However, further controlled studies are needed to standardise protocols and confirm its benefits.
Amanda Karina Santos Vieira   +2 more
wiley   +1 more source

Late Toxicity and Long‐Term Quality of Life in Survivors of Cancer of the Major Salivary Glands More Than 5 Years After Diagnosis: A Multi‐National Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Because salivary gland cancers (SGC) are rare and include different tumor subtypes, data on their long‐term quality of life and late toxicities are sparse. Methods Multi‐national study including SGC survivors more than 5 years after diagnosis.
Susanne Singer   +26 more
wiley   +1 more source

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