Results 71 to 80 of about 2,031,844 (264)
Development of a nalmefene formulation suitable for a community‐use auto‐injector
British Journal of Clinical Pharmacology, EarlyView.Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
Sakarya Tıp Dergisi, 2015 Objectıves: Pulmonary embolism (PE), which has an inflammatory component, has high mortality and morbidity rates. The platelet/lymphocyteratio is a novel marker of inflammation that is an independent predictor of mortality in cardiac and various ...
Ahmet Ertem +8 more
doaj
British Journal of Clinical Pharmacology, EarlyView.Aim To assess the impact of parameter settings when using the individualized dispensing patterns (IDP) method to estimate exposure duration from dispensing data. Methods We conducted a cohort study using a 2% representative sample of the French healthcare insurance database from 2013 to 2022.
Laëtitia Gosselin +8 more
wiley +1 more source
Journal of International Medical ResearchParadoxical embolism refers to thromboemboli originating from the venous system or right heart that traverse an intracardiac or pulmonary shunt into the systemic circulation, causing end-organ embolization.
Yu Chen +4 more
doaj +1 more source
A 27-year-old woman with jaundice and abdominal pain was admitted to an emergency ward. The diagnostic process showed that gallstones were causing her symptoms. The patient was treated via endoscopic retrograde cholangiopancreatography (ERCP), and during
Krzysztof Okoń +5 more
core +1 more source
Clinical Anatomy, EarlyView.ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová +11 more
wiley +1 more source
Annals of Noninvasive ElectrocardiologyThe incidence and mortality rates of acute pulmonary embolism (APE) are high in clinical emergencies, making early diagnosis and risk stratification crucial.
Xue‐Yan Zhang +4 more
doaj +1 more source
Syncope as a presentation of acute pulmonary embolism
, 2016 Bülent Altınsoy, Fatma Erboy, Hakan Tanrıverdi, Fırat Uygur, Tacettin Örnek, Figen Atalay, Meltem Tor Department of Pulmonary Medicine, School of Medicine, Bulent Ecevit University, Kozlu, Zonguldak, Turkey Purpose: Syncope is an atypical ...
Örnek T +6 more
core
, 2017 The pathophysiological topic of acute pulmonary embolism was chosen to increase the knowledge base and provide additional information to assist with moving forward from a registered nurse to an Advance Practicing Nurse. Working as a full-time registered
Fayaz Ahmed +2 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho +12 more
wiley +1 more source