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Pathology of Acute Rejection [PDF]
Experimental cardiac transplantation using various animals preceded the first human-to-human cardiac transplant in 1967. Such experimental work provided a sound basis for our understanding of the clinical and pathological features of cardiac rejection and their modification by immunosuppressive agents.
A. G. Rose, C. J. Uys
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Immune Mechanisms of Acute Rejection
Transplantation Proceedings, 1998An understanding of acute allograft rejection has eluded investigators for many years, despite major research efforts in this area. This understanding may not be achievable, given the current philosophic approach to the study of immune processes. An alternative approach, which is outlined here, would require investigators to develop an appreciation for
A.M VanBuskirk, C.G Orosz
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The challenge of acute rejection in intestinal transplantation [PDF]
Early diagnosis and treatment of acute cellular rejection (ACR) after intestinal transplantation (ITx) is challenging. We report the outcome of three patients: two presented mild ACR improved with steroids. One presented steroid-resistant severe rejection, improved after rabbit anti-thymocyte globulin (r-ATG), but unfortunately died for encephalitis ...
E Y, Yoshitoshi+15 more
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American Journal of Kidney Diseases, 2003
y Dis. 2003;41(1):E31-E32 Fig 1. New evidence has led to re-organization of classification of transplant rejection from a classic, morphological based classification to a mechanistic based classification. Antibodymediated rejection was previously loosely, but not definitely, correlated with the presence of acute glomerulitis, that is the infiltration ...
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y Dis. 2003;41(1):E31-E32 Fig 1. New evidence has led to re-organization of classification of transplant rejection from a classic, morphological based classification to a mechanistic based classification. Antibodymediated rejection was previously loosely, but not definitely, correlated with the presence of acute glomerulitis, that is the infiltration ...
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Signatures Associated with Acute Rejection: Allograft Rejection
2010The physiopathology of immune-mediated tissue injury of acute allograft rejection is not completely understood. Although several mechanicistic experiments have been conducted in vitro and in animal models, only few hypotheses have been confirmed in humans and, paradoxically, findings in humans often lack mechanistic explanations. Before high throughput
Davide Bedognetti, Davide Bedognetti
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Treatment of Acute Antibody-Mediated Rejection
2017Acute antibody-mediated rejection (AMR) remains an important challenge in the field of kidney transplantation despite the advances in immunosuppressive strategies, and has been recognized as an important cause of allograft dysfunction and graft loss.
COMAI, GIORGIA+9 more
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Acute rejection of a cryopreserved arterial homograft
Cell and Tissue Banking, 2014The use of arterial homograft is indicated especially in case of prosthetic graft infections after bypass surgery. We report the case of a patient who experienced the loss of a cryopreserved femoral artery caused by an acute rejection. This homograft had to be explanted 1 month after implantation because of an acute aneurysmal deterioration.
Jérôme Soquet+3 more
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Acute Rejection and Antibody-Mediated Rejection in Lung Transplantation
Clinics in Chest Medicine, 2017Despite advances in immunosuppression over the past 25 years, acute cellular rejection remains a common complication early after lung transplantation. Although acute cellular rejection has often not resulted in clinical signs or symptoms of allograft dysfunction, it has been widely recognized as a strong independent risk factor for the development of ...
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Concomitant Acute Sinusitis and Acute Lung Rejection
Southern Medical Journal, 2000Two lung transplant recipients had concomitant acute sinusitis and acute lung rejection. Antibiotics and decongestants alleviated the sinusitis, but the symptoms of cough and dyspnea as well as spirometric defects necessitated treatment of acute lung rejection.
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