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Diagnosis and Management of Acute Rejection [PDF]
, 2007 Lung transplantation is currently offered as treatment to a variety of end-stage pulmonary diseases such as emphysema, interstitial pulmonary fibrosis, cystic fibrosis, and pulmonary hypertension. The most recent Registry report of the International Society for Heart and Lung Transplantation reveals that more than 4000 lung transplants have been ...
F. M. Wagner, H. Shennib
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Acute rejection after heart transplantation
Expert Opinion on Pharmacotherapy, 2006Acute rejection (AR) seems to be less common with current immunosuppressive strategies; however, it remains a major cause of morbidity and mortality in the first year following heart transplantation. Despite great interest in noninvasive methods for detecting rejection, the endomyocardial biopsy remains the standard method for AR identification and ...
Juan F. Delgado +2 more
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Gross hematuria as a sign of acute rejection
Pediatric Transplantation, 2014AbstractIn the contemporary era of potent immunosuppressive regimens, previously encountered signs of renal allograft rejection such as fever and hematuria are rarely encountered. We report a teenager with severe recurrent acute humoral and cellular rejection whose presenting feature was gross hematuria with the presence of blood clots in the urine. We
Lavjay Butani +2 more
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Pathology of Acute Cellular Rejection
2016Protocol surveillance endomyocardial biopsies are performed to assess for rejection and thus allow the treatment of rejection prior to symptomatic cardiac dysfunction. The biopsies are performed with decreasing frequency post-transplant, usually stopping at 1–3 years post-transplant.
Desley Neil, Alexandra Rice
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Allograft Rejection: Acute and Chronic Studies
2008Organ transplantation represents the only possible therapeutic intervention for a large number of end-stage renal diseases. The current immunosuppressive drugs are very efficient to overcome the acute rejection; however, their continuous administration exposes patients to a great risk of developing opportunistic infections and cancer.
Ariela Benigni +2 more
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Eosinophils in acute renal allograft rejection
Transplant Immunology, 1994Tissue eosinophils have been previously implicated in allograft rejection and graft loss. The aim of this study was to evaluate the role of eosinophils in acute renal allograft rejection. Data from 71 patients with 114 renal biopsies with acute allograft rejection were compared with those from 26 controls.
Leanne F. Avis +5 more
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Acute Rejection, type I (Interstitial) [PDF]
American Journal of Kidney Diseases, 2000 y Dis. 2000;35(4):E13-E14 Fig 1. Tubulitis, ie, infiltration of tubular epithelium by lymphocytes, is the hallmark of type I interstitial acute rejection. Different classifications have been put forth for diagnosis of acute rejection. Among the most widely used are Banff, most recently revised in 1997 (published in Kidney International 1999), and CCTT (
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Acute rejection in vascularized composite allotransplantation
Current Opinion in Organ Transplantation, 2014Acute rejection is the most common complication after vascularized composite allotransplantation (VCA). This review provides a state-of-the-art analysis of prevention, diagnosis and treatment of acute rejection episodes and highlights recent findings with the potential to improve patient care and enhance understanding of the underlying biologic ...
Elazer R. Edelman +10 more
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Diagnosis of Acute Rejection With Cardiac Ultrasound
Transplantation Proceedings, 1998ACUTE rejection (AR) following heart transplantation (HTX) is characterized histologically by patchy or diffuse cellular infiltrates, interstitial oedema, and, if AR is more severe, by myocyte necrosis and hemorrhage. Main criterion for the usefulness of any diagnostic tool is its capability to rapidly and reliably detect AR at the latest stage when ...
Hans-Ulrich Stempfle +5 more
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Acute humoral renal allograft rejection
Current Opinion in Urology, 2002In kidney transplantation, it is well established that donor-specific antibodies can cause substantial graft injury. Hyperacute rejection, now virtually eliminated by routine pretransplant cytotoxic crossmatch testing, represents the prototype of humoral rejection.
Bruno Watschinger +3 more
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