Results 221 to 230 of about 4,859,269 (256)

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Hospital Readmissions in Patients with Severe Acute Respiratory Syndrome: A Retrospective Study in Northeastern Brazil. [PDF]

Diseases
Wanderley RO, Dos Santos CS, Agra KF, Gonçalves FPA, Paes DT, de Brito GB, Lucena GMO, de Carvalho Carriço L, da Silva Junior JR, da Fonseca Lima EJ.   +9 more
europepmc   +1 more source

MXene‐Based Room‐Temperature NO2 Gas Sensors: A Meta‐Analysis

Advanced Science, EarlyView.
This study presents the first comprehensive meta‐analysis of MXene‐based NO2 sensors, decoding 32 study characteristics across 61 peer‐reviewed studies. By isolating materials chemistry as the primary performance driver over device‐level parameters, the authors establish a methodological blueprint and a predictive structure–function map to accelerate ...
Alexander Khort, Jerome Geyer‐Klingeberg, Andreas Rathgeber, Suelen Barg   +3 more
wiley   +1 more source

Mortality and Causes of Death among Individuals in a National Opioid Agonist Treatment Cohort.

Eur Addict Res
Schwarz T, Anzenberger J, Busch M, Schernhammer ES, Strohmaier S.   +4 more
europepmc   +1 more source

Predictive Accuracy of the 1-h HACOR Score for Identifying Non-Invasive Ventilation Failure in COPD Patients With Acute Hypercapnic Respiratory Failure: A Prospective Observational Study. [PDF]

Health Sci Rep
Abedin MJ, Sarker MZH, Wahid MF, Islam MM, Rahman MM, Masuduzzaman SM.   +5 more
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Intensive care unit admission among adults with tuberculosis: a systematic review of clinical characteristics. [PDF]

Crit Care Sci
Stolarz MF, Gomes MF, Pavinati G, Marchiotti MC, Magalhães FB, Magnabosco GT.   +5 more
europepmc   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Does acute inflammation triggered by infection promote cancer progression? [PDF]

PLoS Biol
Valença-Pereira F, Johnson B, DeGregori J, Rincon M.   +3 more
europepmc   +1 more source

Adverse effects of vaping on human health: a brief review of mechanisms and long-term consequences. [PDF]

Arh Hig Rada Toksikol
Fylenko B, Starchenko I, Roiko N.
europepmc   +1 more source